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Merck
모든 사진(3)

주요 문서

D5670

Sigma-Aldrich

Sodium deoxycholate monohydrate

BioXtra, ≥99.0% (titration)

동의어(들):

3α,12α-Dihydroxy-5β-cholanic acid sodium salt, 7-Deoxycholic acid sodium salt, Desoxycholic acid sodium salt

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About This Item

실험식(Hill 표기법):
C24H39NaO4 · H2O
CAS Number:
Molecular Weight:
432.57
Beilstein:
3643164
EC Number:
MDL number:
UNSPSC 코드:
12161900
PubChem Substance ID:
NACRES:
NA.25

설명

anionic

Quality Level

제품 라인

BioXtra

분석

≥99.0% (titration)

양식

powder

광학 활성

[α]20/D +44±2° in H2O(lit.)

분자량

432.57 g/mol

기술

electrophoresis: suitable
immunoprecipitation (IP): suitable

불순물

Insoluble matter, passes filter test
≤0.5% Cholic acid

pH

7.5-9.5 (20 °C, 0.1 M in H2O)

solubility

H2O: 0.1 M, clear, colorless

음이온 미량물

sulfate (SO42-): ≤0.02%

양이온 미량물

Al: ≤0.002%
Ba: ≤0.0005%
Bi: ≤0.0005%
Ca: ≤0.05%
Cd: ≤0.0005%
Co: ≤0.0005%
Cr: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.001%
K: ≤0.010%
Li: ≤0.0005%
Mg: ≤0.002%
Mn: ≤0.0005%
Mo: ≤0.0005%
Ni: ≤0.0005%
Pb: ≤0.0005%
Sr: ≤0.002%
Zn: ≤0.0005%

흡수

≤0.08 at 280 in H2O at 0.1 M
≤0.10 at 260 in H2O at 0.1 M

SMILES string

O.[Na+].C[C@H](CCC([O-])=O)C1CCC2C3CCC4C[C@H](O)CC[C@]4(C)C3C[C@H](O)[C@]12C

InChI

1S/C24H40O4.Na.H2O/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3;;/h14-21,25-26H,4-13H2,1-3H3,(H,27,28);;1H2/q;+1;/p-1/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-;;/m1../s1

InChI key

NDVHNZISGVSFMP-WTCAICSISA-M

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일반 설명

Sodium deoxycholate (SDC) monohydrate is a bile acid salt.

애플리케이션

Powerful solubilization agent; used in the solubilization of estrogen synthetase from human placental microsomes.
Sodium deoxycholate monohydrate has been used in a study to assess a method for the immobilization of lipoxygenase in an alginate-silicate gel matrix. It has also been used in a study to investigate the in vitro dissolution of gall stones.

생화학적/생리학적 작용

Bile Salt

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

예방조치 성명서

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves


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문서 라이브러리 방문

Effect of various lipid-bile salt mixed micelles on the intestinal absorption of amphotericin-B in rat
Dangi, J., et al.
Drug Devel. Ind. Pharm., 24, 631-631 (1998)
R P Modi et al.
Journal of the Indian Medical Association, 89(5), 129-132 (1991-05-01)
An in vitro study on dissolution of 36 gall-stones obtained from 3 patients (12 stones from each patient) was carried out in heparin, bile salt and clofibrate solutions of different strengths. Heparin was found to be a poor solvent while
Liquid crystals and phase equilibria binary bile salt-water systems.
Marques EF, et al.
Langmuir, 16(11), 5178-5186 (2000)
Immobilization of lipoxygenase in an alginate-silicate solgel matrix: formation of fatty acid hydroperoxides
Hsu, A., et al.
Biotechnology Letters, 19, 71-71 (1997)
Suguru Yamasaki et al.
Scientific reports, 9(1), 177-177 (2019-01-19)
During infection, Salmonella senses and responds to harsh environments within the host. Persistence in a bile-rich environment is important for Salmonella to infect the small intestine or gallbladder and the multidrug efflux system AcrAB-TolC is required for bile resistance. The

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