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Merck
모든 사진(1)

주요 문서

E6527

Sigma-Aldrich

Elastin, soluble from bovine neck ligament

salt-free, lyophilized powder

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About This Item

CAS Number:
EC Number:
MDL number:
UNSPSC 코드:
12352202
NACRES:
NA.61

생물학적 소스

bovine neck ligament

Quality Level

형태

salt-free, lyophilized powder

기술

UV/Vis spectroscopy: suitable

UniProt 수납 번호

저장 온도

2-8°C

InChI

1S/C27H48N6O6/c1-9-17(6)23(32-24(36)19(13-15(2)3)30-18(7)34)26(38)29-14-21(35)31-22(16(4)5)27(39)33-12-10-11-20(33)25(37)28-8/h15-17,19-20,22-23H,9-14H2,1-8H3,(H,28,37)(H,29,38)(H,30,34)(H,31,35)(H,32,36)/t17-,19-,20-,22-,23-/m0/s1

InChI key

DPUYCSDGMSDKKV-MKBYFEBXSA-N

유전자 정보

cow ... ELN(280781)

일반 설명

Water-soluble powder prepared by method of Partrige, et al.

애플리케이션

Elastin is a structural protein which has been used in studies of chronic obstructive pulmonary disease (COPD). It may be used to investigate why there is a lack of repair for these proteins in patients with COPD.
Highly stable and hemocompatible protein now finding use in construction of biomaterials as a result of several strategies for its solubilization.

생화학적/생리학적 작용

Protein responsible for the elasticity of many tissues. It is especially important in blood vessels, where it comprises about 50% of the dry tissue weight.

주의사항

Forms coacervate at pH 5.0 and 37 °C

적합성

Suitable for determination of elastolytic activity as described by Keller and Mandi.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


시험 성적서(COA)

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문서 라이브러리 방문

Felix Cleemann et al.
Analytical chemistry, 80(11), 4170-4174 (2008-04-25)
A novel fluorescence polarization assay based on the natural fluorophore epicocconone has been developed. This assay allows the rapid and accurate determination of enzyme kinetic parameters as well as inhibition constants through the measurement of fluorescence anisotropy on the actual
Stefanie Michael et al.
PloS one, 8(3), e57741-e57741 (2013-03-08)
Tissue engineering plays an important role in the production of skin equivalents for the therapy of chronic and especially burn wounds. Actually, there exists no (cellularized) skin equivalent which might be able to satisfactorily mimic native skin. Here, we utilized
A Panagopoulou et al.
Biochimica et biophysica acta, 1834(6), 977-988 (2013-03-27)
Dynamics of uncrystallized water and protein was studied in hydrated pellets of the fibrous protein elastin in a wide hydration range (0 to 23wt.%), by differential scanning calorimetry (DSC), thermally stimulated depolarization current technique (TSDC) and dielectric relaxation spectroscopy (DRS).
J Tong et al.
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 45(4), 364-372 (2013-02-12)
The main purpose of the present study is the investigation of gender differences in the biomechanical properties, thrombus age, mass fraction and key clinical factors of abdominal aortic aneurysms (AAAs). A total of 90 AAA samples (78 males and 12
Wei Li et al.
Arteriosclerosis, thrombosis, and vascular biology, 33(5), 1028-1035 (2013-03-16)
Patients with elastin deficiency attributable to gene mutation (supravalvular aortic stenosis) or chromosomal microdeletion (Williams syndrome) are characterized by obstructive arteriopathy resulting from excessive smooth muscle cell (SMC) proliferation, mural expansion, and inadequate vessel size. We investigated whether rapamycin, an

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