F3388

Ferric citrate

BioReagent, suitable for cell culture

• 동의어(들): Iron(III) citrate, Iron(III) citrate hydrate
• 실험식(Hill 표기법): C₆H₅FeO₇
• CAS Number: 3522-50-7
• Molecular Weight: 244.94
• EC Number: 222-536-6
• MDL number: MFCD00013098
• UNSPSC 코드: 12352205
• PubChem Substance ID: 24894843
• NACRES: NA.75

속성

• 생물학적 소스: synthetic (organic)
• Quality Level: 200
• 제품 라인: BioReagent
• 기술: cell culture | mammalian: suitable
• solubility: hot water: 0.01 g/mL, clear, orange-yellow
• 배송 상태: ambient
• 저장 온도: room temp
• SMILES string: OC12CC(=O)O[Fe](OC(=O)C1)OC2=O
• InChI: 1S/C6H8O7.Fe/c7-3(8)1-6(13,5(11)12)2-4(9)10;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);/q;+3/p-3
• InChI key: NPFOYSMITVOQOS-UHFFFAOYSA-K

설명

애플리케이션

Ferric citrate provides a source of iron used in cell culture applications. It provides iron in a less toxic form than free iron salts. Ferric citrate has been used as medium supplement in human osteosarcoma cell (U2OS) culture, human embryonic kidney (HEK293) cells and adult primary cardiomyocytes.

생화학적/생리학적 작용

Ferric citrate is used as a component of protein-free medium. It is used as a substitute for transferrin in mouse hybridomas culture. Ferric citrate enhances IgM production. It indirectly stimulates the mitogen-activated protein kinase (MAPK) by favoring high amphiregulin oncoprotein levels in colon cancer.  Ferric citrate is effective in binding to phosphate in patients with dialysis-dependent chronic kidney disease.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)