G6013

L-Glutathione reduced

≥98.0%, suitable for cell culture, BioReagent

• 동의어(들): Glutathione, Reduced, γ-L-Glutamyl-L-cysteinyl-glycine, GSH
• Linear Formula: H₂NCH(CO₂H)CH₂CH₂CONHCH(CH₂SH)CONHCH₂CO₂H
• CAS Number: 70-18-8
• Molecular Weight: 307.32
• Beilstein: 1729812
• EC Number: 200-725-4
• MDL number: MFCD00065939
• UNSPSC 코드: 12352209
• PubChem Substance ID: 24895241
• NACRES: NA.26

속성

• 제품명: L-Glutathione reduced, suitable for cell culture, BioReagent, ≥98.0%, powder
• 제품 라인: BioReagent
• Quality Level: 300
• 분석: ≥98.0%
• 양식: powder
• 기술: cell culture | mammalian: suitable
• 색상: white
• mp: 192-195 °C (dec.) (lit.)
• solubility: H₂O: 50 mg/mL
• 저장 온도: 2-8°C
• SMILES string: N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
• InChI: 1S/C10H17N3O6S/c11-5(10(18)19)1-2-7(14)13-6(4-20)9(17)12-3-8(15)16/h5-6,20H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/t5-,6-/m0/s1
• InChI key: RWSXRVCMGQZWBV-WDSKDSINSA-N

설명

Amino Acid Sequence

γ-Glu-Cys-Gly

애플리케이션

May be used at 5-10 mM to elute glutathione S-transferase (GST) from glutathione agarose.

생화학적/생리학적 작용

Endogenous antioxidant that plays a major role in reducing reactive oxygen species formed during cellular metabolism and the respiratory burst. Glutathione-S-transferase catalyzes the formation of glutathione thioethers with xenobiotics, leukotrienes, and other molecules that have an electrophilic center. Glutathione also forms disulfide bonds with cysteine residues in proteins. Via these mechanisms, it can have the paradoxical effect of reducing the efficacy of anti-cancer agents.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)