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Merck
모든 사진(2)

주요 문서

H4014

Sigma-Aldrich

25-Hydroxycholecalciferol

≥98% (HPLC)

동의어(들):

25-Hydroxyvitamin D3

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About This Item

실험식(Hill 표기법):
C27H44O2
CAS Number:
Molecular Weight:
400.64
EC Number:
MDL number:
UNSPSC 코드:
12352205
PubChem Substance ID:
NACRES:
NA.79

Quality Level

분석

≥98% (HPLC)

형태

powder

기술

HPLC: suitable

색상

white to off-white

저장 온도

−20°C

SMILES string

C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C3\C[C@@H](O)CCC3=C

InChI

1S/C27H44O2/c1-19-10-13-23(28)18-22(19)12-11-21-9-7-17-27(5)24(14-15-25(21)27)20(2)8-6-16-26(3,4)29/h11-12,20,23-25,28-29H,1,6-10,13-18H2,2-5H3/b21-11+,22-12-/t20-,23+,24-,25+,27-/m1/s1

InChI key

JWUBBDSIWDLEOM-DTOXIADCSA-N

유전자 정보

human ... VDR(7421)

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애플리케이션


  • Immunoassay development 25-Hydroxycholecalciferol: An investigation into the safety and efficacy of 25-hydroxycholecalciferol produced with Saccharomyces cerevisiae for animal feed emphasized its potential application in developing immunoassays that monitor vitamin D levels in animals, providing a basis for similar applications in human diagnostics (EFSA Panel on Additives and Products, 2023).

생화학적/생리학적 작용

Ergocalciferol (vitamin D2) and 25-Hydroxycholecalciferol (vitamin D3) are the two form of vitamin D which are activated in vivo by hydroxylation. Vitamin D2 and D3 may be used in a wide range of studies to assess their effects on function such as immune function and calcium homeostasis.

픽토그램

Skull and crossbonesHealth hazard

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral - STOT RE 1 Oral

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


시험 성적서(COA)

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Richard McKenzie et al.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 12(9), 1726-1737 (2013-06-29)
To clarify the relation between UV exposure and vitamin D status, 201 volunteers wore personal electronic UV dosimeters during daylight hours, to record their UV exposure over a 10 week period when ambient UV levels were significantly less than the
M Abboud et al.
Endocrinology, 154(9), 3022-3030 (2013-07-05)
Little is known about the mechanism for the prolonged residence time of 25-hydroxyvitamin D (25OHD) in blood. Several lines of evidence led us to propose that skeletal muscle could function as the site of an extravascular pool of 25OHD. In
Jerry Liu et al.
Food chemistry, 140(3), 432-435 (2013-04-23)
There is little information on the vitamin D content of Australian red meat or on the possible influence of latitude on this content. To determine the content of vitamin D3 and 25-hydroxy-vitamin D3 (25OHD3), lamb and beef were analysed from
Julia Höbaus et al.
International journal of cancer, 133(6), 1380-1388 (2013-03-07)
In colorectal cancer (CRC) the vitamin D catabolizing enzyme 1,25-dihydroxyvitamin D 24-hydroxylase (CYP24A1) is overexpressed with a potentially significant, positive impact on the catabolism of 1,25-dihydroxyvitamin D3 (1,25-D3 ). However, the underlying mechanism of CYP24A1 overexpression is poorly understood. In
Bianca Weinstock-Guttman et al.
Journal of neurology, neurosurgery, and psychiatry, 84(11), 1186-1191 (2013-04-19)
To investigate the associations of serum lipid profile with disease progression in high-risk clinically isolated syndromes (CIS) after the first demyelinating event. High density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C) and total cholesterol (TC) were obtained in pretreatment

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