H6503
L-Homocysteine thiolactone hydrochloride
≥98% (TLC)
동의어(들):
L-2-Amino-4-mercaptobutyric acid 1,4-thiolactone hydrochloride
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모든 사진(3)
About This Item
실험식(Hill 표기법):
C4H7NOS · HCl
CAS Number:
Molecular Weight:
153.63
Beilstein:
3911455
EC Number:
MDL number:
UNSPSC 코드:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26
추천 제품
제품명
L-Homocysteine thiolactone hydrochloride, ≥98% (TLC)
Quality Level
분석
≥98% (TLC)
양식
powder
색상
white
mp
185 °C
응용 분야
detection
peptide synthesis
SMILES string
Cl[H].N[C@H]1CCSC1=O
InChI
1S/C4H7NOS.ClH/c5-3-1-2-7-4(3)6;/h3H,1-2,5H2;1H/t3-;/m0./s1
InChI key
ZSEGSUBKDDEALH-DFWYDOINSA-N
유사한 제품을 찾으십니까? 방문 제품 비교 안내
애플리케이션
- Effects of DL-homocysteine thiolactone on cardiac contractility, coronary flow, and oxidative stress markers in the isolated rat heart: This investigation demonstrates the effects of DL-homocysteine thiolactone on heart function, offering insights into its use in cardiovascular research and potential therapeutic applications (Zivkovic et al., 2013).
- Homocysteine is a novel risk factor for suboptimal response of blood platelets to acetylsalicylic acid in coronary artery disease: The study explores how L-homocysteine thiolactone could affect platelet responses in therapy for coronary artery diseases, pointing to its importance in cardiovascular therapeutics (Karolczak et al., 2013).
생화학적/생리학적 작용
L-Homocysteine thiolactone, an amine reactive agent, is used to study post-translational modification of proteins, especially at lysine residues.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
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시험 성적서(COA)
Lot/Batch Number
이미 열람한 고객
Derrick L Sauls et al.
Thrombosis research, 127(6), 576-581 (2011-02-15)
We have shown that homocysteinemic rabbits have altered fibrinogen that forms fibrin clots with increased resistance to fibrinolysis. Homocysteine thiolactone is a metabolite of homocysteine (Hcys) that can react with amines and introduce a new sulfhydryl group into proteins. Recent
Han-Hsin Chang et al.
Molecular vision, 17, 1946-1956 (2011-08-19)
Hyperhomocysteinemia is known to cause degeneration of retinal ganglion cells, but its influence on photoreceptors remains largely unknown. In particular, the role of homocysteine-thiolactone (Hcy-T)--the physiologic metabolite of homocysteine that has been proven to be more cytotoxic than homocysteine itself--as
A Rašić-Marković et al.
Acta physiologica Hungarica, 98(1), 17-26 (2011-03-11)
The aim of our study was to investigate the effects of ifenprodil and MK-801 on D,L-homocysteine thiolactone induced seizures in adult rats.Male Wistar rats were divided into following groups: 1. Saline-treated (C, n=10); 2. D,L-homocysteine thiolactone 8 mmol/kg, i.p. (H
Hieronim Jakubowski
Acta biochimica Polonica, 58(2), 149-163 (2011-06-07)
All living organisms conduct protein synthesis with a high degree of accuracy maintained in the transmission and flow of information from a gene to protein product. One crucial 'quality control' point in maintaining a high level of accuracy is the
Shima Jalili et al.
The protein journal, 30(5), 299-307 (2011-05-17)
Homocysteine thiolactone (HCTL) is a cyclic thioester of homocysteine, showing high reactivity toward lysine residues of proteins. In the present study the structural properties and aggregation propensity of bovine pancreatic insulin were studied in the presences of increasing concentration of
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