I1656

Idarubicin hydrochloride

solid

• 동의어(들): (7S-cis)-9-Acetyl-7-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-5,12-naphthacenedione, 4-Demethoxydaunorubicin hydrochloride, DMDR, IMI-30, Idamycin
• 실험식(Hill 표기법): C₂₆H₂₇NO₉ · HCl
• CAS Number: 57852-57-0
• Molecular Weight: 533.95
• EC Number: 260-990-7
• MDL number: MFCD00866457
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24278488
• NACRES: NA.77

속성

• 양식: solid
• Quality Level: 200
• 주관자: Johnson & Johnson
• 배송 상태: wet ice
• 저장 온도: 2-8°C
• SMILES string: [H][C@@]1(C[C@@](O)(Cc2c(O)c3C(=O)c4ccccc4C(=O)c3c(O)c12)C(C)=O)O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5
• InChI: 1S/C26H27NO9/c1-10-21(29)15(27)7-17(35-10)36-16-9-26(34,11(2)28)8-14-18(16)25(33)20-19(24(14)32)22(30)12-5-3-4-6-13(12)23(20)31/h3-6,10,15-17,21,29,32-34H,7-9,27H2,1-2H3/t10-,15-,16-,17-,21+,26-/m0/s1
• InChI key: XDXDZDZNSLXDNA-TZNDIEGXSA-N
• 유전자 정보: human ... TOP2A(7153)

설명

애플리케이션

Idarubicin is an anthracycline antibiotic that is an anti-leukemia agent with higher DNA binding capacity and greater cytotoxicity than daunorubicin.

생화학적/생리학적 작용

Topoisomerase II inhibitor

특징 및 장점

This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

안전성 정보

• 픽토그램: GHS06,GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H300,H351,H360
• 예방조치 성명서: P201 - P301 + P310 + P330
• Hazard Classifications: Acute Tox. 2 Oral - Carc. 2 - Repr. 1B
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges