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Merck
모든 사진(1)

Key Documents

I5529

Sigma-Aldrich

IgG3, Lambda from human myeloma plasma

purified immunoglobulin, >90% (microfluidic capillary gel electrophoresis)

동의어(들):

Human IgG3-λ

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About This Item

MDL number:
UNSPSC 코드:
12352203
NACRES:
NA.46

생물학적 소스

human

Quality Level

결합

unconjugated

항체 형태

purified immunoglobulin

분석

>90% (microfluidic capillary gel electrophoresis)

배송 상태

dry ice

저장 온도

−20°C

유사한 제품을 찾으십니까? 방문 제품 비교 안내

일반 설명

Identity of IgG3, lambda light chain is verified by subclass monoclonal antibodies and type specific polyclonal antibodies in immunoelectrphoresis and indirect ELISA assays.
IgG antibody subtype is the most abundant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defence of the neonate against infections. IgG3 is the has a unique extended hinge region conferring greater flexibility
IgG3, λ from human myeloma plasma is purified by fractionation, ion-exchange and affinity chromatography.
Mammalian immunoglobins contain either lambda or kappa light chains.

애플리케이션

IgG3, lambda light chain may be used as an antigen for the production and evaluation of antibodies developed for the indentification and classification of IgG3 subtypes. The purified IgG3, lambda may be used as an immunoglobulin calibrator, reference antigen, blocking agent or coating protein in a variety of immunoassays including ELISA, dot-blot immunobinding, Western immunoblotting, immunodiffusion, immunoelectrophoresis, hemagglutination, and cell-binding assays.
The purified IgG3, λ may be used as an immunoglobulin calibrator, reference antigen, blocking agent or coating protein in a variety of immunoassays including ELISA, dot-blot immunobinding, Western immunoblotting, immunodiffusion, immunoelectrophoresis, hemagglutination, and cell-binding assays.

물리적 형태

Solution in 20 mM tris buffered saline, pH 8.0.

분석 메모

The purity and identity are determined by immunoelectrophoresis, indirect ELISA, and SDS-PAGE.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

S Hashira et al.
Pediatrics international : official journal of the Japan Pediatric Society, 42(4), 337-342 (2000-09-15)
Maternal immunoglobulin G (IgG), transferred across the placenta to the fetus during intrauterine life, is an important component of the neonatal immunological defence mechanisms against infection. There is controversy with respect to differences in placental transfer of the different IgG

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