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Merck
모든 사진(1)

주요 문서

L1668

Sigma-Aldrich

Lectin from Phaseolus vulgaris (red kidney bean)

Phytohemagglutinin PHA-P, lyophilized powder (contains ~50% buffer salts as sodium phosphate and NaCl), BioReagent, suitable for cell culture

동의어(들):

Phaseolus vulgaris agglutinin, PHA

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About This Item

UNSPSC 코드:
12352202
NACRES:
NA.32

Quality Level

제품 라인

BioReagent

양식

lyophilized powder (contains ~50% buffer salts as sodium phosphate and NaCl)

효능

≤10 μg per mL mitogenic activity (Bromdeoxyuridine incorporation in human peripheral blood mononuclear cells)

기술

cell culture | mammalian: suitable

색상

white to off-white

solubility

PBS: 5 mg/mL, clear to slightly hazy, colorless to faintly yellow (pH 6.8)

저장 온도

2-8°C

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애플리케이션

Lectin from Phaseolus vulgaris (red kidney bean) has been used:
  • for the stimulation of cluster of differentiation (CD4+) T cells
  • for the activation of primary peripheral blood lymphocytes
  • for the stimulation of peripheral blood mononuclear cells

생화학적/생리학적 작용

PHA consists of two molecular species, an erythroagglutinin (PHA-E) which has low mitogenic activity and high erythroagglutinin activity, and leucoagglutinin (PHA-L) which has high mitogenic and leucoagglutinating activity, but very low erythroagglutinating activity.
PHA-E is not blood group specific, but agglutination can be inhibited by certain oligosaccharides. PHA-P is the protein form of PHA prior to separation and purification of erythroagglutinin and leucoagglutinin. PHA-M is the mucoprotein form. Conjugates are prepared from the corresponding purified lectins.

포장

Sold on the basis of lectin content

분석 메모

Potency and solubility expressed in mg lectin/ml

관련 제품

제품 번호
설명
가격

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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문서 라이브러리 방문

Nina Thakkar et al.
Antimicrobial agents and chemotherapy, 53(2), 631-638 (2008-12-03)
The present studies were conducted to better define the mechanism of action of polyethylene hexamethylene biguanide (PEHMB) (designated herein as NB325), which was shown in previous studies to inhibit infection by the human immunodeficiency virus type 1 (HIV-1). Fluorescence-activated flow
Cellular RelB interacts with the transactivator Tat and enhance HIV-1 expression
Wang M, et al.
Retrovirology, 15(1), 65-65 (2018)
Ema T Crooks et al.
PLoS pathogens, 14(5), e1007024-e1007024 (2018-05-03)
The extensive glycosylation of HIV-1 envelope (Env) glycoprotein leaves few glycan-free holes large enough to admit broadly neutralizing antibodies (bnAb). Consequently, most bnAbs must inevitably make some glycan contacts and avoid clashes with others. To investigate how Env glycan maturation
Marcell Costa de Medeiros et al.
Oncotarget, 8(37), 60860-60874 (2017-10-06)
The immune system detects shifts from homeostasis and eliminates altered cells. However, neoplastic cells can modulate the host response to escape immunosurveillance thereby allowing tumor progression. Head and neck squamous cell carcinoma (HNSCC) is one of the most immunosuppressive cancers
Posttranscriptional Regulation of HIV-1 Gene Expression during Replication and Reactivation from Latency by Nuclear Matrix Protein MATR3
Sarracino A, et al.
mBio, 9(6), e02158-e02118 (2018)

문서

Find the right lectin for your research with our lectin selection guide, organized by lectin source/species, carbohydrate specificity, blood group specificity, and more.

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