L2131

1-Stearoyl-sn-glycero-3-phosphocholine

≥99%, powder

• 동의어(들): L-α-Lysophosphatidylcholine, stearoyl, Lysolecithin, stearoyl
• 실험식(Hill 표기법): C₂₆H₅₄NO₇P
• CAS Number: 19420-57-6
• Molecular Weight: 523.68
• MDL number: MFCD00050427
• UNSPSC 코드: 51191904
• PubChem Substance ID: 24896302
• NACRES: NA.25

속성

• 생물학적 소스: synthetic (organic)
• Quality Level: 200
• 분석: ≥99%
• 양식: powder
• 색상: white
• 작용기: phospholipid
• 지질 유형: phosphoglycerides
• 배송 상태: ambient
• 저장 온도: −20°C
• SMILES string: O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COC(CCCCCCCCCCCCCCCCC)=O
• InChI: 1S/C26H55NO7P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-26(29)32-23-25(28)24-34-35(30,31)33-22-21-27(2,3)4/h25,28H,5-24H2,1-4H3,(H,30,31)
• InChI key: ARQYPVZFUYHQFR-UHFFFAOYSA-N

설명

애플리케이션

<ul>
<li><strong>Plant-derived phenolics inhibit the accrual of structurally characterised protein and lipid oxidative modifications: </strong> Demonstrates the role of 1-Stearoyl-sn-glycero-3-phosphocholine in preventing oxidative modifications in cellular membranes, pertinent to drug delivery systems and cell signaling studies (Soler-Cantero et al., 2012).</li>
</ul>

생화학적/생리학적 작용

1-Stearoyl-sn-glycero-3-phosphocholine (LPC, Lyso-PC) is used in the development of drug transdermal delivery devices such as liposomes and micelles. It inhibits histone deacetylase 3 (HDAC3) activity and signal transducer and activator of transcription 3 (STAT3) phosphorylation and exhibits anticancer activity in chronic myelogenous leukemia (CML) K562 cells.

1-Stearoyl-sn-glycero-3-phosphocholine (LPC, Lyso-PC) is used in the development of drug transdermal delivery devices such as liposomes and micelles.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)