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Merck
모든 사진(5)

주요 문서

L4129

Sigma-Aldrich

L-α-Lysophosphatidylcholine from egg yolk

≥99%, Type I, powder

동의어(들):

1-Acyl-sn-glycero-3-phosphocholine, L-α-Lysolecithin

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About This Item

CAS Number:
EC Number:
MDL number:
UNSPSC 코드:
12352211
NACRES:
NA.25

생물학적 소스

egg yolk

Quality Level

설명

zwitterionic

유형

Type I

분석

≥99%

양식

powder

색상

white

작용기

phospholipid

지질 유형

phosphoglycerides

배송 상태

ambient

저장 온도

−20°C

유사한 제품을 찾으십니까? 방문 제품 비교 안내

애플리케이션

L-α-Lysophosphatidylcholine from egg yolk has been used:
  • as a surfactant
  • as a media supplement and in Staphylococcus aureus inhibition assay in dermatitis
  • as a demyelinating agent for nerve
  • as a component in sperm nuclei preparation buffer

생화학적/생리학적 작용

Lysophosphatidylcholine is a major component of oxidized low density lipoproteins, and has been implicated in various inflammatory reactions, including atherosclerosis. It is used to demyelinate spinal neurons and study the processes underlying remyelination. It activates protein kinase C, p38 MAP kinase, p42 MAP Kinase, and the jun kinase (JNK) pathway, and stimulates transcription of c-jun. Lysophosphatidylcholine accumulates during cardiac ischemia and may induce arrhythmias by uncoupling gap junction communication, and increase ischemic damage by enhancing Na+ loading in cardiac myocytes. It also activates TREK1, TREK2 and TRAAK K+ channels.

품질

Contains primarily palmitic and stearic acids.

제조 메모

Prepared by the action of phospholipase A on egg L-α-phosphatidylcholine.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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문서 라이브러리 방문

Alan Brito Carneiro et al.
PloS one, 8(9), e76233-e76233 (2013-12-07)
Lysophosphatidylcholine (LPC) is the main phospholipid component of oxidized low-density lipoprotein (oxLDL) and is usually noted as a marker of several human diseases, such as atherosclerosis, cancer and diabetes. Some studies suggest that oxLDL modulates Toll-like receptor (TLR) signaling. However
Director configurations in nematic droplets with inhomogeneous boundary conditions
Prishchepa OO, et al.
Physical review. E, 72(3), 031712-031712 (2005)
Transplantation of human skin microbiota in models of atopic dermatitis
Myles IA, et al.
JCI insight, 1(10), 031712-031712 (2016)
N Farrow et al.
Scientific reports, 3, 1287-1287 (2013-02-16)
Genetic therapies for cystic fibrosis (CF) must be assessed for safety and efficacy, so testing in a non-human primate (NHP) model is invaluable. In this pilot study we determined if the conducting airways of marmosets (n = 2) could be
Lauri J Lehto et al.
Frontiers in neuroscience, 11, 433-433 (2017-08-22)
In this work a new MRI modality entitled Relaxation Along a Fictitious Field in the rotating frame of rank 4 (RAFF4) was evaluated in its ability to detect lower myelin content in lysophosphatidyl choline (LPC)-induced demyelinating lesions. The lesions were

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