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1372050

USP

Lysophosphatidylcholine

United States Pharmacopeia (USP) Reference Standard

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Synonym(s):
L-α-Lysophosphatidylcholine from egg yolk, 1-Acyl-sn-glycero-3-phosphocholine, L-α-Lysolecithin
CAS Number:
MDL number:
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

lysophosphatidylcholine

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

−20°C

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Lysophosphatidylcholine USP reference standard for use in specified quality tests and assays.

Also used to prepare standard solution for assay in Egg Phospholipids by Liquid Chromatography in conjunction with evaporative light-scattering detector according to United States Pharmacopeia(USP).

Biochem/physiol Actions

Lysophosphatidylcholine is a major component of oxidized low density lipoproteins, and has been implicated in various inflammatory reactions, including atherosclerosis. It is used to demyelinate spinal neurons and study the processes underlying remyelination. It activates protein kinase C, p38 MAP kinase, p42 MAP Kinase, and the jun kinase (JNK) pathway, and stimulates transcription of c-jun. Lysophosphatidylcholine accumulates during cardiac ischemia and may induce arrhythmias by uncoupling gap junction communication, and increase ischemic damage by enhancing Na+ loading in cardiac myocytes. It also activates TREK1, TREK2 and TRAAK K+ channels.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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