추천 제품
Quality Level
분석
≥98% (HPLC)
양식
solid
색상
white
solubility
DMSO: >5 mg/mL
SMILES string
CC1Nc2cc(Cl)c(cc2C(=O)N1c3ccccc3C)S(N)(=O)=O
InChI
1S/C16H16ClN3O3S/c1-9-5-3-4-6-14(9)20-10(2)19-13-8-12(17)15(24(18,22)23)7-11(13)16(20)21/h3-8,10,19H,1-2H3,(H2,18,22,23)
InChI key
AQCHWTWZEMGIFD-UHFFFAOYSA-N
유전자 정보
human ... SLC12A1(6557) , SLC12A3(6559)
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생화학적/생리학적 작용
Inhibitor of thiazide-sensitive Na+-Cl- cotransporter; antihypertensive; moderate "loop" diuretic.
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
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시험 성적서(COA)
Lot/Batch Number
Jens Rosenberg et al.
Cardiovascular drugs and therapy, 19(4), 301-306 (2005-09-29)
Metolazone is a potent thiazide-like diuretic. It is recommended in severe congestive heart failure (HF). We conducted a review of the existing literature and found that the available information on the use of metolazone in HF is based on studies
Lynda Blue et al.
European journal of heart failure, 7(3), 351-361 (2005-02-19)
This article examines the emerging role of the heart failure nurse and the responsibilities and educational and training requirements surrounding such a role. There may be variations in the role and its responsibilities in different health care settings. However the
[Therapy edema: secondary effect without effect!].
B Truniger
Schweizerische medizinische Wochenschrift, 129(46), 1808-1808 (1999-12-22)
S C Hebert et al.
Kidney international, 49(6), 1638-1641 (1996-06-01)
Recently the molecular identification of the major electroneutral sodium-potassium-chloride entry mechanisms present on apical membranes of distal nephron segments of the mammalian kidney, on basolateral membranes of many non-renal epithelial cells and on certain non-epithelial tissues has been achieved. These
Nigel Sparrow et al.
European journal of heart failure, 5(3), 355-361 (2003-06-12)
The National Service Framework (NSF) sets standards for the management of heart failure in the UK. Loop diuretics are commonly first prescribed in primary care. Some patients taking these drugs have heart failure and may benefit from other treatments including
문서
Voltage-gated sodium channels are present in most excitable cell membranes and play an important role in generating action potentials.
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