추천 제품
분석
≥99%
동작 모드
protein synthesis | interferes
저장 온도
2-8°C
SMILES string
Cl[H].CN1SC=CC1=O
InChI
1S/C4H5NOS.ClH/c1-5-4(6)2-3-7-5;/h2-3H,1H3;1H
InChI key
SJXPQSRCFCPWQQ-UHFFFAOYSA-N
유사한 제품을 찾으십니까? 방문 제품 비교 안내
일반 설명
2-Methyl-4-isothiazolin-3-one hydrochloride (MIT) is a derivative of the synthetic isothiazolinone.
애플리케이션
Methylisothiazolinone (MIT) has been used:
- as a cytotoxic substance to investigate its effect on bronchial epithelial cells (BEAS-2B cells) and its role in apoptotic cell death
- to study the effects of tyrosine phosphorylation on focal adhesion kinase (FAK) activity in the development of neural axons and dendrites
생화학적/생리학적 작용
2-Methyl-4-isothiazolin-3-one hydrochloride (MIT) is a skin sensitizer known to cause contact dermatitis and allergy. It is extensively used in the cosmetic industry as a preservative. MIT is a neurotoxin and its prolonged exposure may lead to neuronal death and inhibition of neurite outgrowth.
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1A - Skin Sens. 1
보충제 위험성
Storage Class Code
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
이미 열람한 고객
Zhenzhen Wang et al.
Biomaterials, 113, 145-157 (2016-11-07)
As common reactive oxygen species, H2O2 is widely used for bacterial inactivation and wound disinfection. However, the concentrations used are always higher than physiological levels, which frequently result in potential toxicity to healthy tissue and even delay wound healing. Here
Siamak Javanbakht et al.
Materials science & engineering. C, Materials for biological applications, 96, 302-309 (2019-01-05)
In compression with the intravenous administration, oral delivery most commonly used due to the non-invasive nature and the fact that avoids patient pain and discomfort. By consideration this aim, ibuprofen as a model drug was loaded into two-dimensional tunnels and
Zhengxi Wei et al.
Toxicology letters, 338, 67-77 (2020-12-09)
Chemical-peptide conjugation is the molecular initiating event in skin sensitization. The OECD test guideline uses a high-performance liquid chromatography/ultraviolet (HPLC/UV) detection method to quantify chemical-peptide conjugation in a direct peptide reactivity assay (DPRA), which measures the depletion of two synthetic
Shen Du et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 22(17), 7408-7416 (2002-08-28)
Neurodegenerative disorders in humans may be triggered or exacerbated by exposure to occupational or environmental agents. Here, we show that a brief exposure to methylisothiazolinone, a widely used industrial and household biocide, is highly toxic to cultured neurons but not
Erol Capkin et al.
Chemosphere, 182, 720-729 (2017-05-23)
Triclosan (TRC), chloroxylenol (PCMX) and methylisothiazolinone (MIT) have been commonly used as an antimicrobial in soaps while borax (BRX) is used in household cleaning. After using these chemicals, they are washed down drains and getting into the aquatic ecosystem in
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