추천 제품
일반 설명
The MOPC-21 tumor line that produces mouse IgG1, κ is a mineral oil induced plasmacytoma originated and carried intraperitoneally in BALB/c mice. Immunoglobulins G are made up of two identical light chains and two identical heavy chains, that are covalently connected by interchain disulphide bonds. Mouse IgG is further divided into five classes- IgG1, IgG2a, IgG2b, IgG2c and IgG3.
애플리케이션
IgG1, Kappa from murine myeloma has been used:
- in stimulation assay and enzyme-linked immunosorbent assay (ELISA)
- as isotype controls in islet hormone production
- in flow cytometric analysis, in cell migration assay
- as control antibody in evaluation of methylation
생화학적/생리학적 작용
IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids. It provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.
Immunoglobulin G (IgG) participates in hypersensitivity type II and type III reactions. IgG helps in opsonization, complement fixation and antibody dependent cell mediated cytotoxicity.
재구성
Reconstitute with 1 mL deionized water.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
The Laboratory Rat (2015)
A Sharland et al.
Transplantation, 65(10), 1370-1377 (1998-06-13)
Liver transplants in the rat strain combination PVG-to-Dark Agouti are spontaneously tolerated, whereas kidney transplants in the same strain combination are rejected in 7-9 days. To identify organ-specific differences that might yield further information about the mechanism of tolerance induction
M-ficolin concentrations in cord blood are related to circulating phagocytes and to early-onset sepsis
Schlapbach LJ, et al.
Pediatric Research, 71(4-1), 368-368 (2012)
Eva Obermueller et al.
Cancer research, 64(21), 7801-7812 (2004-11-03)
Tumor growth and progression are critically controlled by alterations in the microenvironment often caused by an aberrant expression of growth factors and receptors. We demonstrated previously that tumor progression in patients and in the experimental HaCaT tumor model for skin
IL-6 promotes malignant growth of skin SCCs by regulating a network of autocrine and paracrine cytokines
Lederle W, et al.
International Journal of Cancer. Journal International Du Cancer, 128(12), 2803-2814 (2011)
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