콘텐츠로 건너뛰기
Merck
모든 사진(3)

문서

MAK052

Sigma-Aldrich

ALT Activity Assay

sufficient for 100 colorimetric or fluorometric tests

동의어(들):

Alanine Aminotransferase Activity Assay Kit, SGPT Activity Assay Kit, Serum Glutamic-Pyruvic Transaminase Activity Assay Kit

로그인조직 및 계약 가격 보기


About This Item

UNSPSC 코드:
12161503
NACRES:
NA.84

사용

sufficient for 100 colorimetric or fluorometric tests

검출 방법

colorimetric
fluorometric

관련 질환(들)

gastrointestinal diseases

배송 상태

wet ice

저장 온도

−20°C

유전자 정보

human ... GPT(2875)
mouse ... GPT(76282)
rat ... GPT(81670)

일반 설명

Alanine Aminotransferase (ALT), also known as serum glutamic-pyruvic transaminase (SGPT), is a pyridoxal-phosphate-dependent enzyme that catalyzes the reversible transfer of an amino group from alanine to α-ketoglutarate, generating pyruvate and glutamate. ALT is found primarily in liver and serum, but occurs in other tissues as well. Hepatocellular injury often results in an increase of serum ALT levels and serum ALT levels can be used as a marker for liver injury.

애플리케이션

ALT Activity Assay kit has been used to determine the activity of alanine aminotransferase (ALT) in serum samples.

특징 및 장점

Compatible with high-throughput handling systems.

적합성

Suitable for the measurement of alanine aminotransferase (ALT) activity in biological samples including tissue, cells and serum.

원리

The ALT Activity Assay Kit provides a simple and direct procedure for measuring ALT activity in a variety of biological samples.

ALT activity is determined by a coupled enzyme assay, which results in a colorimetric (570 nm)/ fluorometric (λex = 535/λem = 587 nm) product, proportional to the pyruvate generated. One unit of ALT is defined as the amount of enzyme that generates 1.0 μmole of pyruvate per minute at 37 °C.

관련 제품

제품 번호
설명
가격

픽토그램

Health hazard

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Aquatic Chronic 3 - Resp. Sens. 1 - Skin Sens. 1

Storage Class Code

10 - Combustible liquids

WGK

WGK 3


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Investigation of Therapeutic Effects of $\alpha$-Mangostin on Thioacetamide-Induced Cirrhosis in Rats
Nilbunga S.
Journal of the Medical Association of Thailand = Chotmaihet Thangphaet, 98(9), S91-S97 (2015)
L Bočkor et al.
Gene therapy, 24(10), 649-660 (2017-08-15)
Adeno-associated virus (AAV) -mediated gene therapy is a promising strategy to treat liver-based monogenic diseases. However, two major obstacles limit its success: first, vector dilution in actively dividing cells, such as hepatocytes in neonates/children, due to the non-integrating nature of
Melissa F Brereton et al.
Nature communications, 7, 13496-13496 (2016-11-25)
Insulin secretion from pancreatic β-cells is impaired in all forms of diabetes. The resultant hyperglycaemia has deleterious effects on many tissues, including β-cells. Here we show that chronic hyperglycaemia impairs glucose metabolism and alters expression of metabolic genes in pancreatic
Resolvin D1 and E1 alleviate the progress of hepatitis toward liver cancer in long-term concanavalin A-induced mice through inhibition of NF-KB activity.
Kuang H, et al.
Oncology Reports, 35(1), 307-317 (2016)
Nan Wu et al.
Laboratory investigation; a journal of technical methods and pathology, 97(7), 843-853 (2017-06-06)
The Hippo signaling pathway and the Notch signaling pathway are evolutionary conserved signaling cascades that have important roles in embryonic development of many organs. In murine liver, disruption of either pathway impairs intrahepatic bile duct development. Recent studies suggested that

자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..

고객지원팀으로 연락바랍니다.