MAK276

Sulfatase Activity Assay Kit (Colorimetric)

sufficient for 100 colorimetric tests

• UNSPSC 코드: 12161503
• NACRES: NA.84

속성

• 검출 방법: colorimetric
• 관련 질환(들): cancer
• 저장 온도: −20°C

설명

일반 설명

Sulfatases (EC 3.1.6) are a family of enzymes that catalyze the hydrolysis of sulfate ester bonds from a broad range of biological molecules, including steroids, carbohydrates, and proteins. They can be found in intracellular and extracellular spaces and are distributed in a wide range of cells and tissues. Intracellular sulfatases are commonly found localized within the lysosome. Genetic defects in sulfatase can result in certain lysosomal storage disorders and abnormal expression can contribute to certain hormone-dependent cancers, such as breast and prostate cancer.

적합성

Suitable for measuring activity of purified enzyme as well as sulfatase from biological samples.

원리

This Sulfatase Activity Assay Kit provides a quick and easy way to determine sulfatase activity. The kit measures the hydrolysis of a sulfate ester to 4-nitrocatechol, which can be detected at 515 nm. The kit is suitable for measuring activity of purified enzyme as well as sulfatase from biological samples. The limit of detection is below 1 mU.

안전성 정보

• 픽토그램: GHS08,GHS05
• 신호어: Danger
• 유해 및 위험 성명서: H290,H314,H317,H334
• 예방조치 성명서: P234 - P261 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1 - Met. Corr. 1 - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1
• Storage Class Code: 8A - Combustible corrosive hazardous materials