N1415

Naratriptan hydrochloride

≥98% (HPLC)

• 동의어(들): Amerge, GR-85548A, N-Methyl-3-(1-methyl-4-piperidinyl)-1H-indole-5-ethanesulfonamide hydrochloride
• 실험식(Hill 표기법): C₁₇H₂₅N₃O₂S ·HCl
• CAS Number: 143388-64-1
• Molecular Weight: 371.93
• MDL number: MFCD08141821
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329818579
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to off-white
• solubility: H₂O: ≥10 mg/mL
• 주관자: GlaxoSmithKline
• 저장 온도: room temp
• SMILES string: Cl.CNS(=O)(=O)CCc1ccc2[nH]cc(C3CCN(C)CC3)c2c1
• InChI: 1S/C17H25N3O2S.ClH/c1-18-23(21,22)10-7-13-3-4-17-15(11-13)16(12-19-17)14-5-8-20(2)9-6-14;/h3-4,11-12,14,18-19H,5-10H2,1-2H3;1H
• InChI key: AWEZYKMQFAUBTD-UHFFFAOYSA-N
• 유전자 정보: human ... HTR1B(3351) , HTR1D(3352)

설명

생화학적/생리학적 작용

Naratriptan hydrochloride is a serotonin 5-HT_1B/1D receptor agonist.

Naratriptan hydrochloride is a triptan drug that is used to relieve acute migraine headaches. It has poor bioavailability, short half-life, and the incidence of migraine recurrence therefore, it is occasionally used.

특징 및 장점

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H319
• 예방조치 성명서: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable