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Merck
모든 사진(4)

문서

N3877

Sigma-Aldrich

Potassium 4-nitrophenyl sulfate

sulfatase substrate, chromogenic, ≥98% (TLC), powder

동의어(들):

4-Nitrophenyl sulfate potassium salt

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About This Item

Linear Formula:
NO2C6H4OSO2OK
CAS Number:
Molecular Weight:
257.26
Beilstein:
3786392
EC Number:
MDL number:
UNSPSC 코드:
12352204
PubChem Substance ID:
NACRES:
NA.32

product name

Potassium 4-nitrophenyl sulfate, sulfatase substrate

Quality Level

분석

≥98% (TLC)

형태

powder

mp

246-250 °C (lit.)

solubility

water: 50 mg/mL, clear, colorless to very faintly greenish-yellow (to Very Light Yellow)

배송 상태

wet ice

저장 온도

−20°C

SMILES string

[K+].[O-][N+](=O)c1ccc(OS([O-])(=O)=O)cc1

InChI

1S/C6H5NO6S.K/c8-7(9)5-1-3-6(4-2-5)13-14(10,11)12;/h1-4H,(H,10,11,12);/q;+1/p-1

InChI key

BITVAZYUWRLLCN-UHFFFAOYSA-M

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애플리케이션

Potassium 4-nitrophenyl sulfate has been used:
  • as a substrate to measure arylsulfatase activity in cell-free coelomic fluid
  • as a substrate for p-nitrophenyl glycoside-based enzyme assay
  • to inhibit arylsulfatase
  • as an inorganic analog of organic aryl ester sulphate

기질

Chromogenic sulfatase substrate.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


시험 성적서(COA)

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문서 라이브러리 방문

M D Burkart et al.
Analytical biochemistry, 274(1), 131-137 (1999-10-21)
We have developed a continuous spectrophotometric coupled-enzyme assay for sulfotransferase activity. This assay is based on the regeneration of 3'-phosphoadenosine-5'-phosphosulfate (PAPS) from the desulfated 3'-phosphoadenosine-5'-phosphate (PAP) by a recombinant aryl sulfotransferase using p-nitrophenyl sulfate as the sulfate donor and visible
E S Lin et al.
Biochemical and biophysical research communications, 271(3), 818-822 (2000-05-18)
The sulfation of a nucleotide is an indispensable step for the sulfuryl group transfer in a biological system. The product and cosubstrate of sulfotransferase in physiological condition are adenosine 3',5'-bisphosphate (PAP) and 3'-phospho adenosine 5'-phosphosulfate (PAPS), respectively. We find that
A dietary fiber-deprived gut microbiota degrades the colonic mucus barrier and enhances pathogen susceptibility
Desai MS, et al.
Cell, 167(5), 1339-1353 (2016)
Shina Caroline Lynn Kamerlin
The Journal of organic chemistry, 76(22), 9228-9238 (2011-10-11)
Both phosphoryl and sulfuryl transfers are ubiquitous in biology, being involved in a wide range of processes, ranging from cell division to apoptosis. Additionally, it is becoming increasingly clear that enzymes that can catalyze phosphoryl transfer can often cross-catalyze sulfuryl
J O Falkinham
International journal of systematic bacteriology, 40(1), 66-70 (1990-01-01)
A rapid (3-h) arylsulfatase assay for cell suspensions of mycobacteria, in which p-nitrophenyl sulfate is used as the substrate, was developed. Arylsulfatase activity was found in cell suspensions of representative strains of Mycobacterium avium, Mycobacterium intracellulare, and Mycobacterium scrofulaceum grown

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