모든 사진(1)
About This Item
실험식(Hill 표기법):
C175H269N53O54S
CAS Number:
Molecular Weight:
4011.40
MDL number:
UNSPSC 코드:
51111800
NACRES:
NA.32
추천 제품
![[Pro34]-Peptide YY ≥95%](/deepweb/assets/sigmaaldrich/product/images/279/042/6c079852-dc80-45a9-988b-aeb6c84641be/640/6c079852-dc80-45a9-988b-aeb6c84641be.jpg)
Amino Acid Sequence
Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr-NH2
일반 설명
Neuropeptide Y (NPY) is a regulatory protein consisting of 36 amino acids. It is ubiquitously expressed in the heart and brain. NPY is a member of pancreatic polypeptide family. The gene encoding this protein is localized on human chromosome 7p15.
생화학적/생리학적 작용
Endogenous neuropeptide that selectively binds to Y<SUB>2</SUB> and Y<SUB>5</SUB> receptors.
Neuropeptide Y (NPY) plays a vital role in various processes like feeding behavior, anxiety, epilepsy, circadian rhythm, sleep, pain and drug addiction. It also modulates appetite, body weight and obesity. The protein has potent vasoactive effects on the cardiovascular system and controls central endocrine secretion. NPY is involved in the pathogenesis of atherosclerosis and coronary artery disease.
Neuropeptide Y (NPY) plays a vital role in various processes like feeding behavior, anxiety, epilepsy, circadian rhythm, sleep, pain and drug addiction. It also modulates appetite, body weight and obesity. The protein has potent vasoactive effects on the cardiovascular system and controls central endocrine secretion. NPY is involved in the pathogenesis of atherosclerosis and coronary artery disease.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
Eitezaz Mahmood et al.
European journal of pharmacology, 882, 173261-173261 (2020-06-14)
Neuropeptide-Y (NPY) leads to angiogenesis and remodeling of the ischemic myocardium. The objective of this study is to assess the therapeutic potential of NPY in a model of acute myocardial ischemia using a nanoparticles delivery system targeted to tissue with
R Mentlein et al.
Regulatory peptides, 49(2), 133-144 (1993-12-10)
Neuropeptide Y, peptide YY and pancreatic polypeptide share an evolutionary conserved proline-rich N-terminal sequence, a structure generally known to be inert to the attack of common proteinases, but a potential target for specialized proline-specific aminopeptidases. Purified human dipeptidyl peptidase IV
Genetic studies of neuropeptide Y and neuropeptide Y receptors Y1 and Y5 regions in morbid obesity
C Roche
Diabetologia, 40, 671?675-671?675 (1997)
D Grandt et al.
Regulatory peptides, 67(1), 33-37 (1996-11-14)
Neuropeptide Y (NPY 1-36) binds to Y1 and Y2 receptors with similar affinity. No endogenous molecular form of NPY with selectivity for Y1 or Y2 receptors has been described so far. We report the presence of an endogenous fragment of
Neuropeptide Y and sleep.
Dyzma M
Sleep Medicine Reviews, 14(3), 161-165 (2010)
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