P1639

Patulin

≥98.0% (HPLC)

• 동의어(들): Clavacin, Clavatin, Expansine, Gigantin, Leucopin, Mycoine C3, Terinin, 4-Hydroxy-4H-furo[3,2-c]pyran-2(6H)-one
• 실험식(Hill 표기법): C₇H₆O₄
• CAS Number: 149-29-1
• Molecular Weight: 154.12
• Beilstein: 149675
• EC Number: 205-735-2
• MDL number: MFCD00005858
• UNSPSC 코드: 51102829
• PubChem Substance ID: 24898227
• NACRES: NA.85

속성

• Quality Level: 300
• 분석: ≥98.0% (HPLC)
• 양식: powder
• solubility: water: 9-11 mg/mL
• 항생제 활성 스펙트럼: fungi
• 동작 모드: cell membrane | interferes
• 저장 온도: −20°C
• SMILES string: OC1OCC=C2OC(=O)C=C12
• InChI: 1S/C7H6O4/c8-6-3-4-5(11-6)1-2-10-7(4)9/h1,3,7,9H,2H2
• InChI key: ZRWPUFFVAOMMNM-UHFFFAOYSA-N

설명

일반 설명

Patulin is a mycotoxin produced by a variety of molds, such as, Aspergillus and Penicillium. It is commonly found in apples. It is used as an inhibitor of potassium uptake and as an inducer of ion flux across cell membranes, potentially involving Na⁺-K⁺ dependent ATPase and to induce intra- and intermolecular protein crosslinking.

애플리케이션

Patulin has been used:

• to study patulin contamination of bottled wine
• in DNA-damaging activity of patulin in Escherichia coli
• in molecular cloning and functional characterization of two CYP619 cytochrome P450s involved in biosynthesis of patulin in Aspergillus clavatus

생화학적/생리학적 작용

Mycotoxin with anti-bacterial, potassium uptake inhibitory, and possibly carcinogenic activities. It is used as an inhibitor of potassium uptake and as an inducer of ion flux across cell membranes, potentially involving Na⁺-K⁺ dependent ATPase and to induce intra- and intermolecular protein crosslinking.

기타 정보

Keep container tightly closed in a dry and well-ventilated place.

안전성 정보

• 픽토그램: GHS06
• 신호어: Danger
• 유해 및 위험 성명서: H300,H315
• 예방조치 성명서: P264 - P270 - P280 - P301 + P310 - P302 + P352 - P332 + P313
• Hazard Classifications: Acute Tox. 2 Oral - Skin Irrit. 2
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• 개인 보호 장비: Eyeshields, Gloves