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Merck
모든 사진(2)

주요 문서

P4497

Sigma-Aldrich

Anti-Potassium Channel Kv1.3 (extracellular) antibody produced in rabbit

affinity isolated antibody, lyophilized powder

동의어(들):

Anti-Voltage-gated Potassium Channel KV1.3

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About This Item

MDL number:
UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

결합

unconjugated

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

양식

lyophilized powder

종 반응성

human, rat

기술

flow cytometry: 0.5-5 μg
western blot: 1:200-1:500 using rat brain membranes and human Jurkat T lymphocytes.

UniProt 수납 번호

배송 상태

dry ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... KCNA3(3738)
mouse ... Kcna3(16491)
rat ... Kcna3(29731)

관련 카테고리

면역원

synthetic peptide corresponding to amino acid residues 211-224 of human KV1.3. The sequence has 12/14 residues identical in rat and mouse.

물리적 형태

Lyophilized from phosphate buffered saline containing 1% bovine serum albumin and 0.05% sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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시험 성적서(COA)

Lot/Batch Number

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문서 라이브러리 방문

Joseph Andronic et al.
Biochimica et biophysica acta, 1828(2), 699-707 (2012-10-09)
Many functions of T lymphocytes are closely related to cell volume homeostasis and regulation, which utilize a complex network of membrane channels for anions and cations. Among the various potassium channels, the voltage-gated K(V)1.3 is well known to contribute greatly
Andreas Schulte-Mecklenbeck et al.
European journal of immunology, 45(9), 2602-2614 (2015-07-04)
Natural killer (NK) cells are a subset of cytotoxic lymphocytes that recognize and kill tumor- and virus-infected cells without prior stimulation. Killing of target cells is a multistep process including adhesion to target cells, formation of an immunological synapse, and
Weiwei Li et al.
Cancers, 14(11) (2022-06-11)
Pancreas ductal adenocarcinoma (PDAC) is one the most aggressive cancers and associated with very high mortality, requiring the development of novel treatments. The mitochondrial voltage-gated potassium channel, Kv1.3 is emerging as an attractive oncologic target but its function in PDAC
Stella A Nicolaou et al.
Journal of immunology (Baltimore, Md. : 1950), 183(10), 6296-6302 (2009-10-21)
The immunological synapse (IS), a highly organized structure that forms at the point of contact between a T cell and an APC, is essential for the proper development of signaling events, including the Ca(2+) response. Kv1.3 channels control Ca(2+) homeostasis

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