P9797

Pyridostigmine bromide

• 동의어(들): 3-(Dimethylaminocarbonyloxy)-1-methylpyridinium bromide
• 실험식(Hill 표기법): C₉H₁₃BrN₂O₂
• CAS Number: 101-26-8
• Molecular Weight: 261.12
• EC Number: 202-929-9
• MDL number: MFCD00079283
• UNSPSC 코드: 12352200
• PubChem Substance ID: 24277865
• NACRES: NA.77

속성

• 분석: ≥98% (HPLC)
• Quality Level: 100
• 형태: solid
• solubility: water: 100 mg/mL, clear to very slightly hazy, colorless
• 주관자: Valeant
• SMILES string: [Br-].CN(C)C(=O)Oc1ccc[n+](C)c1
• InChI: 1S/C9H13N2O2.BrH/c1-10(2)9(12)13-8-5-4-6-11(3)7-8;/h4-7H,1-3H3;1H/q+1;/p-1
• InChI key: VNYBTNPBYXSMOO-UHFFFAOYSA-M
• 유전자 정보: human ... ACHE(43)

설명

애플리케이션

Pyridostigmine bromide has been used as a cholinesterase inhibitor in mice, in florimetric assay for acetylcholine secretion and for measuring acetylcholine release from mice atrial tissue.

생화학적/생리학적 작용

Pyridostigmine bromide inhibits acetylcholine esterase and is membrane impermeable. It is used as a preventive medicine in chemical warfare. Pyridostigmine bromide is a carbamate compound comprising quaternary amine structure. It displays low absorption at the gastrointestinal tract. Sustained release of pyridostigmine is recommended for improving its bioavailability in treating myasthenia gravis.

Acetylcholinesterase inhibitor.

특징 및 장점

This compound was developed by Valeant. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

안전성 정보

• 픽토그램: GHS06
• 신호어: Danger
• 유해 및 위험 성명서: H300 + H310 + H330,H317
• 예방조치 성명서: P262 - P280 - P301 + P310 + P330 - P302 + P352 + P310 - P304 + P340 + P310
• Hazard Classifications: Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral - Skin Sens. 1
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges