PLA0069
Rabbit anti-RPA70 Antibody, Affinity Purified
Powered by Bethyl Laboratories, Inc.
동의어(들):
70kDa, HSSB, MST075, MSTP075, REPA1, RF-A, RF-A protein 1, RP-A, RP-A p70, RPA70, replication factor A protein 1, replication protein A1, replication protein A1 (70kD), single-stranded DNA-binding protein
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모든 사진(2)
About This Item
UNSPSC 코드:
12352203
NACRES:
NA.41
추천 제품
생물학적 소스
rabbit
Quality Level
항체 형태
affinity purified immunoglobulin
항체 생산 유형
primary antibodies
Grade
Powered by Bethyl Laboratories, Inc.
종 반응성
human, mouse
기술
immunohistochemistry: 1:1,000-1:5,000
immunoprecipitation (IP): 2-10 μg/mg
western blot: 1:2,000-1:10,000
수납 번호(accession number)
NP_002936.1
배송 상태
wet ice
저장 온도
2-8°C
유전자 정보
rabbit ... RPA70(6117)
관련 카테고리
면역원
The epitope recognized by PLA0069 maps to a region between residues 350 and 400 of human replication protein A1, 70kDa using the numbering given in entry NP_002936.1 (GeneID 6117).
물리적 형태
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% sodium azide
기타 정보
Replication protein A (RPA) is a multisubunit complex that carries out DNA mismatch repair (MMR) in association with MSH2 (a subunit of human MutS heterodimers), MLH1 (a subunit of human MutL heterodimers), PCNA, and DNA polymerase-delta. RPA is composed of a heterotrimer that includes subunits of 70 kDa (RPA1), 32kDa (RPA2), and 14kDa (RPA3). RPA1, the 70 kDa subunit, is an ssDNA binding protein that has been shown to be phosphorylated by ATM and ATR in response to DNA damage. In addition to a role in MMR, RPA also functions in the initiation of DNA replication and DNA unwinding at origins of replication.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
12 - Non Combustible Liquids
WGK
nwg
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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