Q2128

Quisqualic acid

powder

• 동의어(들): β-(3,5-Dioxo-1,2,4-oxadiazolidin-2-yl)-L-alanine, 3-(3,5-Dioxo-1,2,4-oxadiazolidin-2-yl)-L-alanine
• 실험식(Hill 표기법): C₅H₇N₃O₅
• CAS Number: 52809-07-1
• Molecular Weight: 189.13
• Beilstein: 1078734
• MDL number: MFCD00069337
• UNSPSC 코드: 12352106
• PubChem Substance ID: 24278004
• NACRES: NA.32

속성

• 형태: powder
• 색상: white to off-white
• solubility: ethanol: <0.17 mg/mL; H₂O: 0.5 mg/mL; 0.1 M HCl: 1.4 mg/mL; 1 M NH4OH: 20 mg/mL; organic solvents: insoluble
• 저장 온도: 2-8°C
• SMILES string: N[C@@H](CN1OC(=O)NC1=O)C(O)=O
• InChI: 1S/C5H7N3O5/c6-2(3(9)10)1-8-4(11)7-5(12)13-8/h2H,1,6H2,(H,9,10)(H,7,11,12)/t2-/m0/s1
• InChI key: ASNFTDCKZKHJSW-REOHCLBHSA-N
• 유전자 정보: rat ... Gria1(50592) , Grik1(29559) , Grin2a(24409) , Grm1(24414) , Grm2(24415) , Grm4(24417) , Grm5(24418)

설명

일반 설명

Quisqualate/ Quisqualic acid is obtained from the fruits and seeds of Quisqualis chinensis. It is an agonist at two subsets of excitatory amino acid receptors metabotropic receptors that indirectly mediate calcium mobilization from intracellular stores and, ionotropic receptors that directly control membrane channels. L-quisqualic acid is an agonist of the neurotransmitter L-glutamate.

애플리케이션

Quisqualic acid has also been used as a group I metabotropic receptor agonist in neurons.

Quisqualic acid has been used to test ligand-gated receptors in spiral ganglion neurons.

생화학적/생리학적 작용

Active enantiomer of quisqualic acid; excitatory amino acid at glutamate receptors.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves