추천 제품
종 반응성
mouse
포장
kit of 96 wells (12 strips x 8 wells)
기술
ELISA: suitable
capture ELISA: suitable
입력
sample type cell lysate
sample type tissue lysate
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 5 pg/mL
standard curve range: 2.74-2000 pg/mL
검출 방법
colorimetric
배송 상태
wet ice
저장 온도
−20°C
유전자 정보
mouse ... Il1b(16176)
일반 설명
The Mouse IL-1 β ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of mouse IL-1 β cell lysate and tissue lysate.
면역원
Recombinant Mouse IL-1 β
애플리케이션
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Mouse IL-1 β ELISA Kit has been used to measure the concentration of interleukin 1 (IL)1-β in serum and bronchoalveolar lavage fluid (BALF) sample.
생화학적/생리학적 작용
Interleukin 1 β (IL-1β) stimulates the production of endogenous 92 kDa gelatinase (matrix metalloproteinases 9 (MMP-9)) and tissue inhibitors of MMP (TIMP -1). It is a proinflammatory cytokine that induces various acute and chronic inflammation. Therefore, IL-1β can be considered as a potential therapeutic target for disease associated with fibrosis and tissue remodeling. IL-1β brings neutrophil and macrophage to the site of infection. Over expression of IL-1β in synovial fluid contributes to the pathogenesis of synovitis and degenerative changes of the cartilaginous tissue and bone of the temporomandibular joint. Mutations in IL-1β gene leads to renal manifestations and renal sequelae in Henoch-Schonlein purpura (HSP).
기타 정보
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
키트 구성품 역시 별도로 이용 가능함
제품 번호
설명
SDS
신호어
Warning
유해 및 위험 성명서
예방조치 성명서
Hazard Classifications
Met. Corr. 1
Storage Class Code
8A - Combustible corrosive hazardous materials
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Protective effects of fucoidan against hyperoxic lung injury via the ERK signaling pathway
Nie M, et al.
Molecular Medicine Reports, 17(1), 1813-1818 (2018)
Inactivation of the tyrosine phosphatase SHP-2 drives vascular dysfunction in Sepsis
Heun Y, et al.
EBioMedicine (2019)
Proinflammatory cytokines detectable in synovial fluids from patients with temporomandibular disorders
Takahashi T, et al.
Oral Surgery, Oral Medicine, and Oral Pathology, 85(2), 135-141 (1998)
Strain- and host species-specific inflammasome activation, IL-1? release, and cell death in macrophages infected with uropathogenic Escherichia coli.
Schaale K
Mucosal Immunology, 9(1), 124-136 (2016)
Differential regulation of monocyte matrix metalloproteinase and TIMP-1 production by TNF-alpha, granulocyte-macrophage CSF, and IL-1 beta through prostaglandin-dependent and -independent mechanisms.
Zhang Y
Journal of Immunology, 161(6), 3071-3076 (1998)
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.