추천 제품
종 반응성
rat
포장
kit of 96 wells (12 strips x 8 wells)
기술
ELISA: suitable
입력
sample type cell culture supernatant(s)
sample type serum sample(s)
sample type plasma
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 20 pg/ml
검출 방법
colorimetric
배송 상태
wet ice
저장 온도
−20°C
유전자 정보
rat ... Timp2(29543)
일반 설명
Tissue inhibitor of metalloproteinase 2 (TIMP -2) is expressed in the brain especially in spinal motor neurons, cerebellar Purkinje cells, cerebral cortical, and hippocampal pyramidal cells. It is an inhibitor of matrix metalloproteinase and tumor angiogenesis. TIMP-2 is involved in matrix remodeling and stimulates quiescent cell proliferation. This ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of a target protein in biological samples, such as serum, plasma, cell culture supernatants, urine, and/or cell and tissue lysates.
애플리케이션
For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.
Please refer to the attached Protocolfor details.
Rat TIMP-2 ELISA Kit has been used in enzyme-linked immunosorbent assay to quantify tissue inhibitor of metalloproteinase 2 (TIMP -2) in U87MG human glioblastoma cells.
기타 정보
A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.
신호어
Warning
유해 및 위험 성명서
예방조치 성명서
Hazard Classifications
Met. Corr. 1
Storage Class Code
8A - Combustible corrosive hazardous materials
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
Diane M Jaworski et al.
Journal of neurochemistry, 98(1), 234-247 (2006-06-30)
Neuronal differentiation requires exquisitely timed cell cycle arrest for progenitors to acquire an appropriate neuronal cell fate and is achieved by communication between soluble signals, such as growth factors and extracellular matrix molecules. Here we report that the expression of
Dimitra Bourboulia et al.
Oncotarget, 4(1), 166-176 (2013-02-02)
Tissue Inhibitor of Metalloproteinase 2 (TIMP-2) plays an essential role in regulating matrix remodeling, cell growth, differentiation, angiogenesis and apoptosis in vitro and in vivo. We have recently shown that TIMP-2-mediated inhibition of tumor growth is independent of matrix metalloproteinase-mediated
Dong-Wan Seo et al.
Cell, 114(2), 171-180 (2003-07-31)
Tissue inhibitors of metalloproteinases (TIMPs) suppress matrix metalloproteinase (MMP) activity critical for extracellular matrix turnover associated with both physiologic and pathologic tissue remodeling. We demonstrate here that TIMP-2 abrogates angiogenic factor-induced endothelial cell proliferation in vitro and angiogenesis in vivo
Shan Wu et al.
International journal of molecular medicine, 42(6), 3386-3394 (2018-10-03)
The present study investigated the underlying molecular mechanism by which Buthus martensii Karsch chlorotoxin (BmK CT) inhibits the invasion and metastasis of glioma cells and the possibility of 131I‑labeled BmK CT (131I‑BmK CT) as a novel targeted agent for the treatment of glioma. The
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