모든 사진(1)
About This Item
실험식(Hill 표기법):
C9H12ClNO3S
CAS Number:
Molecular Weight:
249.71
MDL number:
UNSPSC 코드:
51111800
PubChem Substance ID:
NACRES:
NA.32
추천 제품
양식
solid
Quality Level
색상
white
solubility
0.1 M NaOH: 20 mg/mL
SMILES string
NCC(CS(O)(=O)=O)c1ccc(Cl)cc1
InChI
1S/C9H12ClNO3S/c10-9-3-1-7(2-4-9)8(5-11)6-15(12,13)14/h1-4,8H,5-6,11H2,(H,12,13,14)
InChI key
JYLNVJYYQQXNEK-UHFFFAOYSA-N
유전자 정보
human ... GABBR1(2550) , GABBR2(9568)
mouse ... GABBR1(54393) , GABBR2(242425)
rat ... GABBR1(81657) , GABBR2(83633)
애플리케이션
Saclofen has been used as a GABAB receptor antagonist to study the analgesic effect of repeated injections of oxycodone in rats.
Saclofen has been used to prevent the inhibitory action of oxytocin on capsaicin-induced glutamatergic spontaneous excitatory transmission in rat neurons.
생화학적/생리학적 작용
Saclofen is the sulphonic analog of baclofen and is a selective GABAB receptor antagonist.
Saclofen might possess sympathetic nervous system-dependent anti-inflammatory action.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
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European journal of pharmacology, 525(1-3), 69-73 (2005-11-22)
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