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Merck
모든 사진(4)

Key Documents

S7635

Sigma-Aldrich

Sulforhodamine 101

Dye content ~95 %, Powder

동의어(들):

SR101; 2-(3-oxa-23-aza-9-azoniaheptacyclo[17.7.1.15,9.02,17.04,15.023,27.013,28]octacosa-1(27),2(17),4,9(28),13,15,18-heptaen-16-yl)-5-sulfobenzenesulfonate

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About This Item

실험식(Hill 표기법):
C31H30N2O7S2
CAS Number:
Molecular Weight:
606.71
Beilstein:
3582548
EC Number:
MDL number:
UNSPSC 코드:
12171500
PubChem Substance ID:
NACRES:
NA.47

product name

Sulforhodamine 101, Dye content ~95 %

형태

powder

구성

Dye content, ~95%

색상

black
dark green to brown

solubility

methanol: 1 mg/mL

ε (흡광계수)

≥105000 at 573-579 nm in ethanol

형광

λex 586 nm; λem 605 nm in H2O

응용 분야

diagnostic assay manufacturing
hematology
histology

저장 온도

room temp

SMILES string

OS(=O)(=O)c1ccc(C2=C3C=C4CCC[N+]5=C4C(CCC5)=C3Oc6c7CCCN8CCCc(cc26)c78)c(c1)S([O-])(=O)=O

InChI

1S/C31H30N2O7S2/c34-41(35,36)20-9-10-21(26(17-20)42(37,38)39)27-24-15-18-5-1-11-32-13-3-7-22(28(18)32)30(24)40-31-23-8-4-14-33-12-2-6-19(29(23)33)16-25(27)31/h9-10,15-17H,1-8,11-14H2,(H-,34,35,36,37,38,39)

InChI key

COIVODZMVVUETJ-UHFFFAOYSA-N

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일반 설명

Sulforhodamine 101 is a red fluorescent dye. It is water-soluble, amphoteric rhodamine.

애플리케이션

Sulforhodamine 101 has been used:
  • to label astrocytes
  • in quantitative polymerase chain reaction (PCR)
  • to determine the degree of disintegration in tissue sample

생화학적/생리학적 작용

Sulforhodamine 101 can be specifically used as a marker of astroglia in the neocortex. It is commonly used for brain imaging. Studies suggest that sulforhodamine 101 may be used as an epileptogenic agent.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


시험 성적서(COA)

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

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Scientific reports, 9(1), 3791-3791 (2019-03-09)
A comprehensive understanding of the stimulus-response properties of individual neurons is necessary to crack the neural code of sensory cortices. However, a barrier to achieving this goal is the difficulty of analysing the nonlinearity of neuronal responses. Here, by incorporating
Danielle Tokarz et al.
PloS one, 12(10), e0186846-e0186846 (2017-10-25)
Osteocytes are the most abundant cell in the bone, and have multiple functions including mechanosensing and regulation of bone remodeling activities. Since osteocytes are embedded in the bone matrix, their inaccessibility makes in vivo studies problematic. Therefore, a non-invasive technique
Sulforhodamine 101 as a specific marker of astroglia in the neocortex in vivo
Nimmerjahn A, et al.
Nature Methods, 1(1), 31-31 (2004)
Florence Appaix et al.
PloS one, 7(4), e35169-e35169 (2012-04-18)
Fluorescent staining of astrocytes without damaging or interfering with normal brain functions is essential for intravital microscopy studies. Current methods involved either transgenic mice or local intracerebral injection of sulforhodamine 101. Transgenic rat models rarely exist, and in mice, a

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