F6377

Fluorescein sodium salt

Powder

• 동의어(들): Acid Yellow 73, D&C;Yellow No. 8, NaFl, NaFluo, Sodium fluorescein, Uranine
• 실험식(Hill 표기법): C₂₀H₁₀Na₂O₅
• CAS Number: 518-47-8
• Molecular Weight: 376.27
• 색상 지수 번호: 45350
• Beilstein: 3833041
• EC Number: 208-253-0
• MDL number: MFCD00167039
• UNSPSC 코드: 12171500
• PubChem Substance ID: 24894907
• NACRES: NA.47

속성

• 제품명: Fluorescein sodium salt, used as fluorescent tracer
• Quality Level: 200
• 양식: powder
• 기술: titration: suitable
• pH: 8.3 (20 °C, 10 g/L)
• mp: >300 °C
• solubility: H₂O: 1 mg/mL
• density: 0.78 g/cm³ at 29.6 °C (85.3 °F at 699.7 hPa)
• 형광: λ_ex 460 nm; λ_em 515 nm(lit.)
• 응용 분야: diagnostic assay manufacturing; hematology; histology

설명

일반 설명

Fluorescein is a xanthene dye and is a common labeling agent in biology.[1]

애플리케이션

Fluorescein sodium salt has been used as a solute to study microvessel permeability.[2][3] It has been used as a test molecule to study blood barrier penetration.[4]

Water soluble fluorescent dye used in permeability and vascular perfusion studies due to its small molecular radius.[5] Sodium fluorescein is used as a fluorescent tracer to study blood-brain barrier (BBB) and blood-spinal cord barrier (BSCB) permeability in rodent models.[6][7][8] The dye was used as a probe substrate in the study of organic anion transporting polypeptide (OATP) mediated drug transport in hepatocytes.[9] Sodium fluorescein was also used to monitor in situ solute transportation into bone through fluorescence recovery after photobleaching (FRAP).[10]

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): 423.7 °F - Pensky-Martens closed cup
• Flash Point (°C): 217.6 °C - Pensky-Martens closed cup
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)