추천 제품
생물학적 소스
goat
Quality Level
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
형태
buffered aqueous solution
종 반응성
mouse, rat, human
기술
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable
UniProt 수납 번호
배송 상태
dry ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... AIF1(199)
일반 설명
AIF1 (allograft inflammatory factor 1) is a calcium-binding, cytoplasmic protein that has 143-amino acids. It is also known as IBA1 (ionized calcium-binding adapter molecule 1). It is expressed in the cells of the monocyte/macrophage lineage, as well as in microglial and dendritic cells. It is located on human chromosome 6p21.3.
면역원
Peptide with sequence C-NKQFLDDPKYSSDED from the internal region of the protein sequence according to NP_001614.3.
애플리케이션
Anti-AIF1/IBA1 (Isoform 3) antibody produced in goat has been used in western blotting and immunofluorescence.
생화학적/생리학적 작용
AIF1 (allograft inflammatory factor 1) is an essential factor of macrophage chemotaxis. Expression of AIF1 regulates the proliferation of vascular smooth muscle cells by G-CSF (cytokine granulocyte-colony stimulating factor) autocrine expression.
특징 및 장점
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
물리적 형태
Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Dorsal root ganglia in Friedreich ataxia: satellite cell proliferation and inflammation.
Arnulf H K, et al.
Acta Neuropathologica Communications, 4(1), 46-46 (2016)
Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment.
Wang Q, et al.
Cancer Cell, 32(1), 42-56 (2017)
Inhibition of AIF-1 expression by constitutive siRNA expression reduces
macrophage migration, proliferation, and signal transduction initiated by
atherogenic stimuli.
macrophage migration, proliferation, and signal transduction initiated by
atherogenic stimuli.
Ying T, et al.
American Journal of Physiology. Cell Physiology (2005)
dolescent binge alcohol exposure affects the brain function through mitochondrial impairment
Tapia-Rojas C, et al.
Molecular Neurobiology, 55, 4473-4491 (2018)
Azhaar Ahmad Ashraf et al.
Frontiers in aging neuroscience, 16, 1393351-1393351 (2024-06-05)
Iron dyshomeostasis and neuroinflammation, characteristic features of the aged brain, and exacerbated in neurodegenerative disease, may induce oxidative stress-mediated neurodegeneration. In this study, the effects of potential priming with mild systemic iron injections on subsequent lipopolysaccharide (LPS)-induced inflammation in adult
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