SAB2702145

Monoclonal Anti-ESR2 antibody produced in mouse

• 동의어(들): ESRB, ESTRB, Erb, NR3A2
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: mouse
• Quality Level: 100
• 결합: unconjugated
• 항체 형태: purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: 14C8; monoclonal
• 양식: liquid
• 분자량: 58-60 kDa
• 종 반응성: mouse, human, monkey
• 농도: 1 mg/mL
• 기술: ChIP: suitable; dot blot: suitable; flow cytometry: suitable; immunocytochemistry: suitable; immunofluorescence: suitable; immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable; western blot: 1:1000-1:10000
• 동형: IgG2b
• UniProt 수납 번호: Q92731
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... ESR2(2100)

설명

면역원

Amino acids 1-153 of human ER-beta expressed in E. coli.

애플리케이션

Suggested starting dilutions are as follows: Dot: Assay-dependent dilution, FACS: Assay-dependent dilution, ICC/IF: Assay-dependent dilution, IHC: Assay-dependent dilution, IHC-P: Assay-dependent dilution, WB: 1:1000-1:10000, ChIP assay: Assay-dependent dilution. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.

생화학적/생리학적 작용

The human ER-beta is a newly discovered estrogen receptor initially cloned and characterized from testis. The size and structure of ER-beta is very similar to ER-alpha with the ligand and DNA binding domains being highly conserved, while the amino terminus which serves as their transactivation domain has diverged significantly. Similar in function to ER-alpha ER-beta binds to estrogen with a high affinity and regulates estrogen specific gene activation through direct interaction with estrogen response elements (ERE′s).

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

Phosphate-buffered saline, no preservative added.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable