추천 제품
생물학적 소스
rabbit
Quality Level
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
형태
buffered aqueous solution
분자량
antigen 66 kDa
종 반응성
rat, mouse, human
농도
~1 mg/mL
기술
ELISA: 1:20000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... ESR1(2099)
일반 설명
Anti-Estrogen Receptor-α Antibody detects endogenous levels of total Estrogen Receptor-α protein.
Estrogen receptor alpha (ERα) is a member of the nuclear receptor superfamily. It is also known as ESR1 (estrogen receptor). It is located on human chromosome 6q25.1.
면역원
The antiserum was produced against synthesized peptide derived from human Estrogen Receptor-alpha.
Immunogen Range: 71-120
Immunogen Range: 71-120
생화학적/생리학적 작용
Estrogen receptor alpha (ERα) is involved in immune and inflammatory response. Aberrations in ESR1 results in Mayer-Rokitansky-Küster-Hauser syndrome that is associated with the congenital absence of the uterus and the upper two-thirds of the vagina.
특징 및 장점
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
물리적 형태
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
nwg
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
ER?36, a variant of estrogen receptor ?, is predominantly localized in mitochondria of human uterine smooth muscle and leiomyoma cells
PLoS ONE, 12(10) (2017)
ESR1 is co-expressed with closely adjacent uncharacterised genes spanning a breast cancer susceptibility locus at 6q25.1
PLoS Genetics, 7(4) (2011)
Amplification of WHSC1L1 regulates expression and estrogen-independent activation of ER? in SUM-44 breast cancer cells and is associated with ER? over-expression in breast cancer
Molecular Oncology, 10(6), 850-865 (2016)
Ratio of Circulating Estrogen Receptors Beta and Alpha (ERβ/ERα) Indicates Endoscopic Activity in Patients with Crohn's Disease
Digestive Diseases and Sciences, 62(10), 2744-2754 (2017)
Sequence variants in ESR1 and OXTR are associated with Mayer-Rokitansky-Kuster-Hauser syndrome
Acta Obstetricia et Gynecologica Scandinavica, 96(11), 1338-1346 (2017)
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