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Merck
모든 사진(2)

Key Documents

SAB4200673

Sigma-Aldrich

Monoclonal Anti-α-Amylase 1A antibody produced in mouse

clone AMY-7, purified from hybridoma cell culture

동의어(들):

AMY1, AMY1A, alpha 1A (salivary), amylase

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

mouse

Quality Level

항체 형태

purified immunoglobulin

항체 생산 유형

primary antibodies

클론

AMY-7, monoclonal

형태

buffered aqueous solution

분자량

~58 kDa

종 반응성

human, rat, mouse

농도

~1 mg/mL

기술

immunoblotting: 0.25-0.5 μg/mL using rat pancreas tissue extracts.
immunohistochemistry: 5-10 μg/mL using heat-retrieved formalin-fixed, paraffin-embedded human pancreas sections.

동형

IgG1

배송 상태

dry ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... AMY1A(276)
mouse ... Amy1(11722)
rat ... Amy1a(24203)

일반 설명

Monoclonal Anti- α-Amylase 1A (mouse IgG1 isotype) is derived from the hybridoma AMY-7 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with an N-terminal His-tagged recombinant human α. α-Amylase 1A, also known as AMY1A belongs to the α-Amylase family. AMY1A is a secreted digestive enzyme produced by the salivary glands and pancreas.

면역원

N-terminal His-tagged recombinant human α-Amylase 1A.

애플리케이션

Monoclonal Anti-α-Amylase 1A antibody has been used in immunoblotting, immunohistochemistry.

생화학적/생리학적 작용

α-Amylase 1A cleaves the glycosidic linkages in starch molecules to produce smaller saccharides such as maltotriose, maltose, and small amounts of glucose. AMY1A has been identified as an indicator in pancreas and salivary gland diseases, as well as lung cancer, ovarian cancer, plasmacytoma and thyroid adenomas.

물리적 형태

Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Subsite mapping of human salivary alpha-amylase and the mutant Y151M
Kandra L, et al.
Febs Letters, 544(1-3), 194-198 (2003)
Expression of alpha-amylase isozymes in human thyroid tissues
Doi S, et al.
Cancer research, 51(13), 3544-3549 (1991)
Paola Serrano Martinez et al.
Oral diseases, 27(1), 52-63 (2020-06-13)
Hyposalivation-related xerostomia is an irreversible, untreatable, and frequent condition after radiotherapy for head and neck cancer. Stem cell therapy is an attractive option of treatment, but demands knowledge of stem cell functioning. Therefore, we aimed to develop a murine parotid
Xian Zhang et al.
Developmental cell, 57(12), 1496-1511 (2022-06-09)
Diabetic patients show elevated plasma IL18 concentrations. IL18 has two receptors: the IL18 receptor (IL18r) and the Na-Cl co-transporter (NCC). Here, we report that IL18 is expressed on islet α cells, NCC on β cells, and IL18r on acinar cells

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