SAB4200762

Anti-Opsin antibody, Mouse monoclonal

clone RET-P1, purified from hybridoma cell culture

• 동의어(들): Anti-Opsin 2, Anti-Rhodopsin
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: mouse
• Quality Level: 200
• 항체 형태: purified from hybridoma cell culture
• 항체 생산 유형: primary antibodies
• 클론: RET-P1, monoclonal
• 양식: buffered aqueous solution
• 분자량: ~39 kDa
• 종 반응성: avian, bovine, fish, mouse, rat, human, amphibian, turtle, rabbit
• 농도: ~1 mg/mL
• 기술: ELISA: suitable; immunoblotting: 2-4 μg/mL using human retinoblastoma Y79 cell line extract. ; immunofluorescence: suitable; immunohistochemistry: 5-10 μg/mL using rat eye frozen sections.; radioimmunoassay: suitable
• 동형: IgG1
• UniProt 수납 번호: P08100
• 배송 상태: dry ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: rat ... Rho(24717)

설명

일반 설명

Anti-Opsin antibody, Mouse monoclonal (rhodopsin) (mouse IgG1 isotype) is derived from the RET-P1 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from BALB/C mice immunized with rat retinal membranes. Opsin is also called as rhodopsin protein, members of the G-protein coupled receptor (GPCR) superfamily. Opsin comprises >95% of the rod outer segments (ROS) intrinsic membrane and consists of a protein moiety - an opsin - and a non-protein moiety - the chromophore retinal.

애플리케이션

Anti-Opsin antibody has been used in

• immunoblotting
• immunofluorescence
• immunohistochemistry
• enzyme linked immunosorbent assay (ELISA)
• radioimmuno assay (RIA)

생화학적/생리학적 작용

Opsin is an essential molecules for mediating the ability of animals to detect and use light for diverse biological functions. Mutations in the opsin (rhodopsin) gene are linked to retinitis pigmentosa (RP), a disease characterized by retinal degeneration resulting in reduced peripheral vision and night blindness.

기타 정보

rat retinal membranes

물리적 형태

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable