SAB4501894

Anti-MMP-7 antibody produced in rabbit

affinity isolated antibody

• 동의어(들): MMP-7, Matrilysin, Matrix metalloproteinase-7, Pump-1 protease, Uterine metalloproteinase
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 형태: buffered aqueous solution
• 분자량: antigen 29 kDa
• 종 반응성: human, mouse, rat
• 농도: ~1 mg/mL
• 기술: ELISA: 1:5000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI 수납 번호: P09237
• UniProt 수납 번호: P09237
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... MMP7(4316)

설명

일반 설명

Anti-MMP-7 Antibody detects endogenous levels of total MMP-7 protein.

Matrix metalloproteinase-7 (MMP7) is also termed as matrilysin. It is located on human chromosome 11q21-->q22. It belongs to the MMP enzyme family and is highly expressed in cancer cells. MMP7 is exclusively released by epithelial cells.

면역원

The antiserum was produced against synthesized peptide derived from human MMP-7.

Immunogen Range: 218-267

애플리케이션

Anti-MMP-7, C-Terminal antibody has been used in immunofluorescence.

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunofluorescence (1 paper)

생화학적/생리학적 작용

Overexpression of matrix metalloproteinase-7 (MMP7) is observed in various cancers, such as breast, lung, prostate, esophagus, stomach, endometrium, and ovarian carcinomas, as well as esophageal squamous cell carcinomas. Activated MMP7 plays a vital role in human colorectal cancer (CRC) liver metastases. It is essential for the development of tumor in the absence of PKP3 (plakophilin3).

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: nwg
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable