추천 제품
생물학적 소스
rabbit
Quality Level
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
양식
buffered aqueous solution
분자량
antigen 126 kDa
종 반응성
human
농도
~1 mg/mL
기술
ELISA: 1:1000
western blot: 1:500-1:1000
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... TERT(7015)
일반 설명
Anti-Telomerase Antibody detects endogenous levels of total Telomerase protein.
The TERT (telomerase reverse transcriptase) gene is mapped to human chromosome 5p15.33 and encodes for a ribonucleoprotein.
면역원
The antiserum was produced against synthesized peptide derived from human Telomerase.
Immunogen Range: 796-845
Immunogen Range: 796-845
생화학적/생리학적 작용
TERT (telomerase reverse transcriptase) catalyzes the de novo synthesis of telomere and results in cellular immortalization to maintain chromosomal stability. Mutations in TERT causes different types of malignancies such as gliomas, gastric cancer, and anaplastic thyroid cancer. Therefore, TERT serves as an early prognostic biomarker.
특징 및 장점
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
물리적 형태
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
nwg
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
Human telomerase reverse transcriptase (hTERT) promotes gastric cancer invasion through cooperating with c-Myc to upregulate heparanase expression.
Oncotarget, 7(10), 11364-11379 (2016)
Brain regions associated with telomerase reverse transcriptase promoter mutations in primary glioblastomas.
Journal of Neuro-Oncology, 28(3), 455-462 (2016)
Silencing of hTERT blocks growth and migration of anaplastic thyroid cancer cells.
Molecular and Cellular Endocrinology, 448, 34-40 (2017)
Lung cancer susceptibility locus at 5p15.33.
Nature Genetics, 40(12), 1404-1406 (2008)
The role of TERT-CLPTM1L SNPs, hTERT expression and telomere length in the pathogenesis of oral squamous cell carcinoma.
Journal of Oral Science, 58(4), 449-458 (2016)
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