추천 제품
생물학적 소스
rabbit
Quality Level
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
형태
buffered aqueous solution
분자량
antigen 24 kDa
종 반응성
human, mouse
농도
~1 mg/mL
기술
ELISA: 1:5000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... CLDN2(9075)
관련 카테고리
일반 설명
Anti-Claudin 2 Antibody detects endogenous levels of total Claudin 2 protein.
Claudin-2 is one of the pore-forming claudins. It is a member of the claudin family of proteins. Claudin-2 is present in the proximal tubules. It is mapped to human chromosome Xq22.
면역원
The antiserum was produced against synthesized peptide derived from human Claudin 2.
Immunogen Range: 181-230
Immunogen Range: 181-230
애플리케이션
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)
Immunohistochemistry (1 paper)
생화학적/생리학적 작용
The tetraspan membrane protein encoded by claudin multigene controls paracellular permeability and maintaining cell polarity in epithelial and endothelial cell sheets. In MDCK (madin-darby canine kidney cells) II cells, claudin-2 participates in the generation of aqueous pores with high conductance.
특징 및 장점
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
물리적 형태
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
nwg
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Conversion of Zonulae Occludentes from Tight to Leaky Strand Type by Introducing Claudin-2 into Madin-Darby Canine Kidney I Cells
Furuse M, et al.
The Journal of Cell Biology, 153(2), 263-272 (2001)
The claudins
Lal-Nag M and Morin P J
Genome Biology (2009)
Inga B Christensen et al.
Frontiers in physiology, 4, 344-344 (2013-12-19)
The choroid plexus epithelium (CPE) has served as a model-epithelium for cell polarization and transport studies and plays a crucial role for cerebrospinal fluid (CSF) production. The normal luminal membrane expression of Na(+),K(+)-ATPase, aquaporin-1 and Na(+)/H(+) exchanger 1 in the
Inhibition of Autophagic Degradation Process Contributes to Claudin-2 Expression Increase and Epithelial Tight Junction Dysfunction in TNF-? Treated Cell Monolayers
Zhang C, et al.
International Journal of Molecular Sciences, 18(1) (2017)
Tumor necrosis factor-? induces a biphasic change in claudin-2 expression in tubular epithelial cells: role in barrier functions
Amoozadeh Y, et al.
American Journal of Physiology. Cell Physiology, 309(1), C38-C50 (2015)
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