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Merck
모든 사진(3)

문서

SAB4503583

Sigma-Aldrich

Anti-CD4 antibody produced in rabbit

affinity isolated antibody

동의어(들):

CD4, T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4 precursor

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

rabbit

결합

unconjugated

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

형태

buffered aqueous solution

분자량

antigen 51 kDa

종 반응성

human, mouse

농도

~1 mg/mL

기술

ELISA: 1:1000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

NCBI 수납 번호

UniProt 수납 번호

배송 상태

wet ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... CD4(920)

관련 카테고리

일반 설명

Anti-CD4 Antibody detects endogenous levels of total CD4 protein.
CD4 (CD4 molecule) is present in the surface of specific leukocytes. CD4 contains four ecto-domains (D1-D4) of which D1, D2, and D4 contain disulfide bonds. It is mapped to human chromosome 12p13.31.

면역원

The antiserum was produced against synthesized peptide derived from human CD4.

Immunogen Range: 401-450

애플리케이션

Anti-CD4, C-Terminal antibody has been used in immunohistochemical staining.

생화학적/생리학적 작용

CD4 (CD4 molecule) helps in the activation of immunostimulatory T-cells. It serve as a primary receptor for HIV-1 entry.This molecule plays an important role on cell membrane mechanical characteristics and can be used in the development of cell biology and medicine.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

Fang Zhang et al.
Frontiers in immunology, 10, 2392-2392 (2019-11-05)
Background: Stroke patients with diabetes suffer from higher mortality rate and worsened neurological outcome. However, the responses of immune system to cerebral ischemia in the setting of diabetes remain poorly understood. Methods: In this study, we investigated the temporal profile
M I Ashraf et al.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 16(3), 808-820 (2015-11-26)
Lipocalin 2 (Lcn2) is rapidly produced by damaged nephron epithelia and is one of the most promising new markers of renal injury, delayed graft function and acute allograft rejection (AR); however, the functional importance of Lcn2 in renal transplantation is
Exogenous Lipocalin 2 Ameliorates Acute Rejection in a Mouse Model of Renal Transplantation
Ashraf MI, et al.
American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 16(3), 808-820 (2016)
The role of CD4 on mechanical properties of live cell membrane
Bui VC and Nguyen TH
Journal of Biomedical Materials Research Part A, 104(1), 239-244 (2016)
Human CD4 Metastability Is a Function of the Allosteric Disulfide Bond in Domain 2
Owen GR, et al.
Biochemistry, 55(15), 2227-2237 (2016)

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