추천 제품
생물학적 소스
rabbit
Quality Level
재조합
expressed in proprietary host
결합
unconjugated
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
SP162, monoclonal
종 반응성
human (tested)
종 반응성(상동성에 의해 예측)
rat, chicken, rabbit, mouse, pig, bovine, dog
기술
flow cytometry: 1:150
immunoblotting: 1:150
immunohistochemistry: 1:150
동형
IgG
UniProt 수납 번호
배송 상태
wet ice
저장 온도
2-8°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... CD3E(916)
관련 카테고리
일반 설명
CD3E (CD3e molecule) gene is mapped to human chromosome 11q23.3. This gene encodes fora subunit of T-cell regulator (TCR) protein complex. It possesses IgG (immunoglobulin G)-like extracelluar domain at the N-terminal, a transmembrane domain, a peptide bridge and an immunoreceptor tyrosine-based activation motif (ITAM) towards the cytoplasm. The protein also contains basic residue-rich sequence (BRS).
This antibody reacts with the intracytoplasmic portion of the CD3 antigen expressed by T cells. It stains human T cells in both the cortex and medulla of the thymus and in peripheral lymphoid tissues. This antibody is suitable for staining normal and neoplastic T cells in formalin-fixed, paraffin-embedded tissues.
면역원
Synthetic peptide corresponding to internal region of the epsilon chain of human CD3 protein.
애플리케이션
Anti-CD3 antibody, Rabbit monoclonal has been used in immunohistochemistry.
생화학적/생리학적 작용
CD3E (CD3e molecule) gene is associated with actin cytoskeletal rearrangement, through activation of a number of signaling pathways. CD3E is essential for membrane binding of T-cell regulator (TCR) protein complex.
특징 및 장점
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
물리적 형태
0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
이미 열람한 고객
Evidence for inducible recruitment of Wiskott-Aldrich syndrome protein to T cell receptor-CD3 complex in Jurkat T cells
Paensuwan P, et al.
Asian Pacific Journal of Allergy and Immunology / Launched by the Allergy and Immunology Society of Thailand, 33(3) (2015)
SnapShot: forkhead transcription factors II
Tuteja G and Kaestner KH
Cell, 131(1), 192-192 (2007)
Ionic CD3- Lck interaction regulates the initiation of T-cell receptor signaling
Li L, et al.
Proceedings of the National Academy of Sciences of the USA, 114(29), E5891-E5899 (2017)
Xuan He et al.
Cell, 184(13), 3467-3473 (2021-06-17)
We previously reported that a single immunization with an adenovirus serotype 26 (Ad26)-vector-based vaccine expressing an optimized SARS-CoV-2 spike (Ad26.COV2.S) protected rhesus macaques against SARS-CoV-2 challenge. To evaluate reduced doses of Ad26.COV2.S, 30 rhesus macaques were immunized once with 1 ×
The progression of CD56+ myeloid sarcoma: A case report and literature review
Wang X, et al.
Oncology Letters, 11(5), 3091-3096 (2016)
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