추천 제품
재조합
expressed in HEK 293 cells
Quality Level
항체 형태
purified immunoglobulin
항체 생산 유형
primary antibodies
클론
RM224, monoclonal
recombinant monoclonal
양식
buffered aqueous glycerol solution
종 반응성
human
농도
~1 mg/mL
기술
ELISA: 0.2- 1 μg/mL
immunoblotting: 0.5-2 μg/mL
immunocytochemistry: 0.5-2 μg/mL
동형
IgG
NCBI 수납 번호
배송 상태
wet ice
저장 온도
−20°C
타겟 번역 후 변형
phosphorylation (pSer139)
유전자 정보
human ... H2AX(3014)
일반 설명
Histone H2AX (H2A histone family member X), a histone variant present in almost all eukaryotes, is coded by H2AFX gene. It is mapped to human chromosome 11q23.2–11q23.3.
특이성
This antibody reacts to Histone H2A.X only when phosphorylated at serine 139. No cross reactivity with other phosphorylated histones.
면역원
Synthetic peptide corresponding to Phospho-Histone H2AX (Ser139)
생화학적/생리학적 작용
H2AX (H2A histone family member X) helps to maintain genome stability. It plays an important role in localisation and structuring of the repair focus. H2AX also plays an active role in supplying the active repair proteins. γH2AX participates in DSB repair. This protein serves as a signal and target of phosphorylation in the spreading phase.
특징 및 장점
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
물리적 형태
Solution in phosphate buffered saline containing 50% glycerol, 1% BSA and 0.09% sodium azide.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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