SAB5700016

Anti-PARP1 antibody produced in rabbit

• 동의어(들): ADPRT, ADPRT 1, ADPRT1, ARTD1, Cleaved PARP, PARP, PARP-1, PARP1, PPOL, pADPRT-1
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 형태: buffered aqueous solution
• 분자량: 113
• 종 반응성: rat, human, mouse
• 농도: 2.78 mg/ml
• 기술: ChIP: 1:50-1:200; immunofluorescence: 1:50-1:200; immunohistochemistry: 1:50-1:200; immunoprecipitation (IP): 1:50-1:200; western blot: 1:1000-1:3000
• UniProt 수납 번호: P09874
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... PARP1(142)

설명

일반 설명

This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

면역원

Recombinant fusion protein containing a sequence corresponding to amino acids 81-390 of human PARP1 (NP_001609.2).

물리적 형태

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

저장 및 안정성

Store at -20℃. Avoid freeze / thaw cycles.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable