SAB4500487

Anti-PARP (Cleaved-Asp²¹⁴) antibody produced in rabbit

affinity isolated antibody

• 동의어(들): ADP-ribosyltransferase 1, ADPRT, ADPRT1, PARP, pADPRT-1
• UNSPSC 코드: 12352203
• NACRES: NA.41
• 결합: unconjugated
• application: ELISA; WB
• 클론: polyclonal
• 종 반응성: mouse, human
• citations: 12
• 기술: ELISA: 1:20000; western blot: 1:500-1:1000

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 결합: unconjugated
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 양식: buffered aqueous solution
• 분자량: antigen 24 kDa
• 종 반응성: mouse, human
• 농도: ~1 mg/mL
• 기술: ELISA: 1:20000; western blot: 1:500-1:1000
• NCBI 수납 번호: P09874
• UniProt 수납 번호: P09874
• 배송 상태: wet ice
• 저장 온도: −20°C
• 타겟 번역 후 변형: proteolytically cleaved (Asp214)
• 유전자 정보: human ... PARP1(142)

설명

일반 설명

Anti-PARP (Cleaved-Asp²¹⁴) Antibody detects endogenous levels of fragment of activated PARP (Cleaved-Asp²¹⁴) protein.

PARP1 (poly (ADP-ribose) polymerase 1) is a nuclear protein that consists of three functional domains. It belongs to the PARP family. It is located on chromosome 1q42.

면역원

The antiserum was produced against synthesized peptide derived from human PARP.

Immunogen Range: 165-214

애플리케이션

Anti-PARP (Cleaved-Asp214) antibody has been used in Western Blotting.

생화학적/생리학적 작용

PARP1 (poly (ADP-ribose) polymerase 1) participates in DNA repair. It serves as a facilitator of homologous recombination. It controls transcription by regulating chromatin structure, altering DNA methylation patterns, acting as a co-regulator of transcription factors and interacting with chromatin insulators. It also plays an important role in the protection of cardiovascular system.

특징 및 장점

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

물리적 형태

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: nwg
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable