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Merck
모든 사진(1)

문서

PLA0184

Sigma-Aldrich

Rabbit anti-PARP1 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

동의어(들):

ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase), ADP-ribosyltransferase NAD(+), ADP-ribosyltransferase diphtheria toxin-like 1, ADPRT, ADPRT 1, ADPRT1, ARTD1, NAD(+) ADP-ribosyltransferase 1, PARP, PARP-1, PPOL, member 1, pADPRT-1, poly (ADP-ribose) polymerase 1, poly (ADP-ribose) polymerase family, poly(ADP-ribose) polymerase, poly(ADP-ribose) synthetase, poly(ADP-ribosyl)transferase, poly[ADP-ribose] synthase 1

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모든 사진(1)

About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

100

항체 형태

affinity purified immunoglobulin

항체 생산 유형

primary antibodies

Grade

Powered by Bethyl Laboratories, Inc.

종 반응성

human

기술

western blot: 1:2,000-1:10,000

수납 번호(accession number)

NP_001609.1

UniProt 수납 번호

P09874

배송 상태

wet ice

저장 온도

2-8°C

타겟 번역 후 변형

unmodified

유전자 정보

rabbit ... PARP1(142)

면역원

The epitope recognized by PLA0184 maps to a region between residue 1 and 50 of human poly (ADP-ribose) polymerase family, member 1 using the numbering given in entry NP_001609.1 (GeneID 142).

물리적 형태

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

기타 정보

PARP1 (Poly-ADP-ribose polymerase 1) is a member of PARP family of enzymes that transfer the ADP-D-ribosyl group of NAD(+) to an acceptor carboxyl group on proteins. PARP1 catalyzes the poly-ADP-ribosylation of histone and non-histone proteins in response to DNA damage. The over-activation of PARP-1 in response to DNA damage has been shown to promote cell and tissue injury. This observation has initiated research into the therapeutic potential of PARP1 inhibitors in the treatment of cancer, cardiovascular disease, and brain injury.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

시험 성적서(COA)

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