추천 제품
Quality Level
분석
≥95% (LC/MS-ELSD)
양식
solid
응용 분야
metabolomics
vitamins, nutraceuticals, and natural products
저장 온도
−20°C
SMILES string
O1[C@@H]([C@H](c4c1cc(cc4\C=C\c5ccc(cc5)O)O)c3c(cc(cc3)O)O)c2ccc(cc2)O
InChI
1S/C28H22O6/c29-19-7-2-16(3-8-19)1-4-18-13-22(32)15-25-26(18)27(23-12-11-21(31)14-24(23)33)28(34-25)17-5-9-20(30)10-6-17/h1-15,27-33H/b4-1+/t27-,28+/m0/s1
InChI key
KQXXUMAWOUVEHD-BQYFGGCBSA-N
일반 설명
Natural product derived from plant source.
애플리케이션
Viniferin has been used to study its effect on melanin production in melanocyte cultures.
생화학적/생리학적 작용
Protein Huntingtin (Htt) mutation, reduces the SIRT3 (sirtuin 3) expression. Viniferin is known to offer protection against Htt mutation by reducing oxidative stress and preventing SIRT3 depletion, which is involved in energy metabolism. In vitro analysis showed that viniferin derivative could prevent amyloid β peptide aggregation.
신호어
Warning
유해 및 위험 성명서
예방조치 성명서
Hazard Classifications
Aquatic Acute 1 - Aquatic Chronic 1
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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이미 열람한 고객
trans-(−)-ε-Viniferin increases mitochondrial sirtuin 3 (SIRT3), activates AMP-activated protein kinase (AMPK), and protects cells in models of Huntington Disease
Fu J, et al.
The Journal of Biological Chemistry, 287(29) (2012)
Aude Pflieger et al.
PloS one, 8(11), e81184-e81184 (2013-12-07)
Polynucleotidyl transferases are enzymes involved in several DNA mobility mechanisms in prokaryotes and eukaryotes. Some of them such as retroviral integrases are crucial for pathogenous processes and are therefore good candidates for therapeutic approaches. To identify new therapeutic compounds and
Protective effect of varepsilon-viniferin on beta-amyloid peptide aggregation investigated by electrospray ionization mass spectrometry
Richard T, et al.
Bioorganic & Medicinal Chemistry, 19(10) (2011)
Advances in Chorea Research and Treatment (2013)
α-Viniferin Improves Facial Hyperpigmentation via Accelerating Feedback Termination of cAMP/PKA-Signaled Phosphorylation Circuit in Facultative Melanogenesis.
Yun C Y, et al.
Theranostics, 8(7), 2031-2031 (2018)
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