SML0864

EMPA

≥98% (HPLC)

• 동의어(들): N-Ethyl-2-[(6-methoxy-3-pyridinyl)[(2-methylphenyl)sulfonyl]amino]-N-(3-pyridinylmethyl)-acetamide
• 실험식(Hill 표기법): C₂₃H₂₆N₄O₄S
• CAS Number: 680590-49-2
• Molecular Weight: 454.54
• UNSPSC 코드: 51111800
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: film
• 색상: white to light brown
• 저장 온도: −20°C
• SMILES string: [S](=O)(=O)(N(CC(=O)N(CC)Cc3cnccc3)c2cnc(cc2)OC)c1c(cccc1)C
• InChI: 1S/C23H26N4O4S/c1-4-26(16-19-9-7-13-24-14-19)23(28)17-27(20-11-12-22(31-3)25-15-20)32(29,30)21-10-6-5-8-18(21)2/h5-15H,4,16-17H2,1-3H3
• InChI key: KJPHTXTWFHVJIG-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

EMPA is a potent, selective OX2R antagonist (IC₅₀ = 2.3 nM). EMPA binds reversibly to OX2R and inhibits orexin-a and -b-evoked intracellular calcium flux in cells expressing recombinant OX2R, but not OX1R.

물리적 형태

This product is solubilized for packaging and then dried down for shipment. It would appear as a lyophilized powder or film on the vial. Solvent should be added directly to the vial to prepare their sample for testing.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302
• 예방조치 성명서: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable