SML2593

MS0021570

≥98% (HPLC)

• 동의어(들): 5-(Benzylsulfanyl)-N-methyl-1,3,4-thiadiazol-2-amine, 5-(Benzylthio)-N-methyl-1,3,4-thiadiazol-2-amine, MS 21570, MS0021570_1, N-Methyl-5-[(phenylmethyl)thio]-1,3,4-thiazadiazol-2-amine
• 실험식(Hill 표기법): C₁₀H₁₁N₃S₂
• CAS Number: 65373-29-7
• Molecular Weight: 237.34
• MDL number: MFCD01018163
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to beige
• solubility: DMSO: 2 mg/mL, clear
• 저장 온도: 2-8°C
• SMILES string: [s]1c(nnc1NC)SCc2ccccc2
• InChI: 1S/C10H11N3S2/c1-11-9-12-13-10(15-9)14-7-8-5-3-2-4-6-8/h2-6H,7H2,1H3,(H,11,12)
• InChI key: KFLNRVSOQJTXDG-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

GPR171 antagonist

MS0021570 is a potent antagonist of GPR171, a G protein-coupled receptor of BigLEN (b-LEN), which is a neuropeptide derived from proSAAS and involved in regulation of feeding. MS0021570 had a IC50 value of 220 nM. It was shown to block inceases in food intake and to reduce anxiety-like behavior and fear conditioning in mice.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable