SML3207
MB05032
≥98% (HPLC)
동의어(들):
2-Amino-5-isobutyl-4-[5-phosphono-2-furanyl]thiazole, 5-[2-Amino-5-(2-methylpropyl)-4-thiazolyl]-2-furanyl]phosphonic acid, CS-917 active drug, MB 05032, MB-05032, MB-06322 active drug, MB06322 active drug, [5-[2-Amino-5-(2-methylpropyl)-1,3-thiazol-4-yl]furan-2-yl]phosphonic acid
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모든 사진(1)
About This Item
실험식(Hill 표기법):
C11H15N2O4PS
CAS Number:
Molecular Weight:
302.29
MDL number:
UNSPSC 코드:
12352200
NACRES:
NA.77
추천 제품
Quality Level
분석
≥98% (HPLC)
양식
powder
색상
white to beige
solubility
DMSO: 2 mg/mL, clear (warmed)
저장 온도
−20°C
SMILES string
[P](=O)(O)(O)c1[o]c(cc1)c2nc([s]c2CC(C)C)N
InChI
1S/C11H15N2O4PS/c1-6(2)5-8-10(13-11(12)19-8)7-3-4-9(17-7)18(14,15)16/h3-4,6H,5H2,1-2H3,(H2,12,13)(H2,14,15,16)
InChI key
XJMYIJPPDSZOPN-UHFFFAOYSA-N
생화학적/생리학적 작용
MB05032 is an AMP site-targeting, potent and selective fructose-1,6-bisphosphatase (FBPase) inhibitor (rec hum liver FBPase IC50 = 16 nM, purified hum muscle/rat liver FBPase IC50 = 29/61 nM) with no potency toward glycogen phosphorylase or AMP-activated protein kinase. MB05032 inhibits cellular (rat/human hepotocytes IC50/glucose gluconeogenesis (GNG) substrate = 7.8 ?M/lactate & pyruvate/rat hepotocytes, 47.5 μM/lactate/human hepotocytes).
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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