SML3500
Colesevelam hydrochloride
≥98% (HPLC)
동의어(들):
1-Hexanaminium, N,N,N-trimethyl-6-(2-propenylamino)-, chloride, polymer with (chloromethyl)oxirane, 2-propen-1-amine and N-2-propenyl-1-decanamine, hydrochloride, 2-Propen-1-amine, polymer with (chloromethyl)oxirane, N-2-propenyl-1-decanamine and N,N,N-trimethyl-6-(2-propenylamino)-1-hexanaminium chloride, hydrochloride, CholestaGel, Colesevelam HCl, GT 31-104
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모든 사진(1)
About This Item
Linear Formula:
(C13H27N.C12H27N2.C3H7N.C3H5ClO.Cl)x.xHCl
CAS Number:
UNSPSC 코드:
12352200
NACRES:
NA.21
추천 제품
Quality Level
분석
≥98% (HPLC)
형태
powder
분자량
581.79 g/mol
저장 조건
desiccated
색상
white to beige
저장 온도
-10 to -25°C
SMILES string
C=CCNCCCCCCCCCC.C=CCNCCCCCC[N+](C)(C)C.NCC=C.ClCC1OC1.[xHCl].[Cl-]
생화학적/생리학적 작용
Colesevelam hydrochloride, a polyamine polymer, is an oral, non-absorbed bile acid sequestrant. Colesevelam hydrochloride absorbs bile acids in the intestine, which increases demand for cholesterol synthesis and affectively lowers low-density lipoprotein cholesterol (LDL-C) blood levels.
주의사항
Hygroscopic
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Sanjay Kalra et al.
JPMA. The Journal of the Pakistan Medical Association, 70(5), 934-936 (2020-05-14)
Colesevelam is a bile acid sequestrant, approved for the management of both dyslipidaemia and type 2 diabetes. This review discusses the potential for the use of colesevelam in the management of type 2 diabetes. Expert opinion suggests possible indications where
Phillipp Hartmann et al.
Hepatology international, 16(2), 359-370 (2022-01-26)
Obesity, non-alcoholic fatty liver disease (NAFLD) and its more advanced form non-alcoholic steatohepatitis (NASH) are important causes of morbidity and mortality worldwide. Bile acid dysregulation is a pivotal part in their pathogenesis. The aim of this study was to evaluate
Noemí Cabré et al.
Cells, 10(6) (2021-07-03)
Alcohol-related liver disease is associated with intestinal dysbiosis. Functional changes in the microbiota affect bile acid metabolism and result in elevated serum bile acids in patients with alcohol-related liver disease. The aim of this study was to identify the potential
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