SML3523
Solriamfetol hydrochloride
≥98% (HPLC)
동의어(들):
(2R)-2-Amino-3-phenylpropyl carbamate hydrochloride, (R)-2-amino-3-phenylpropylcarbamate hydrochloride, ADX-N 05, ADX-N05, JZP 110, JZP-110
로그인조직 및 계약 가격 보기
모든 사진(1)
About This Item
실험식(Hill 표기법):
C10H14N2O2 ·HCl
CAS Number:
Molecular Weight:
230.69
MDL number:
UNSPSC 코드:
12352200
NACRES:
NA.04
추천 제품
Quality Level
분석
≥98% (HPLC)
형태
powder
약물 제어
USDEA Schedule IV
저장 조건
desiccated
색상
white to beige
solubility
DMSO: 2 mg/mL, clear
저장 온도
2-8°C
생화학적/생리학적 작용
Solriamfetol (JZP-110) is a potent and selective dual reuptake inhibitor at dopamine and norepinephrine transporters that increases extracellular levels of dopamine and norepinephrine in vivo. Solriamfetol is a wake-promoting agent.
주의사항
Hygroscopic
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Richard K Bogan et al.
Sleep medicine, 16(9), 1102-1108 (2015-08-25)
JZP-110 is a wake-promoting agent with dopaminergic and noradrenergic activity. This double-blind, crossover study, randomized adults with narcolepsy with or without cataplexy (N = 33) to placebo or JZP-110 at 150 mg/day (weeks 1 and 3) increased to 300 mg/day (weeks 2 and 4).
Michelle G Baladi et al.
The Journal of pharmacology and experimental therapeutics, 366(2), 367-376 (2018-06-13)
Excessive sleepiness (ES) is associated with several sleep disorders, including narcolepsy and obstructive sleep apnea (OSA). A role for monoaminergic systems in treating these conditions is highlighted by the clinical use of US Food and Drug Administration-approved drugs that act
Stefano de Biase et al.
Expert opinion on investigational drugs, 26(8), 953-963 (2017-07-21)
Narcolepsy is a chronic sleep disorder characterized by a pentad of excessive daytime sleepiness (EDS), cataplexy, sleep paralysis, hypnagogic/hypnopompic hallucinations, and disturbed nocturnal sleep. While non-pharmacological treatments are sometimes helpful, more than 90% of narcoleptic patients require a pharmacological treatment.
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